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Bile acids induce visceral hypersensitivity via mucosal mast cell-to-nociceptor signaling that involves the farnesoid X receptor/nerve growth factor/transient receptor potential vanilloid 1 axis.
Li WT, Luo QQ, Wang B, Chen X, Yan XJ, Qiu HY, Chen SL. Li WT, et al. Among authors: chen sl, chen x. FASEB J. 2019 Feb;33(2):2435-2450. doi: 10.1096/fj.201800935RR. Epub 2018 Sep 27. FASEB J. 2019. PMID: 30260705
In this study, we tested the hypothesis that BAs cause VH via mucosal mast cell (MMC)-to-nociceptor signaling, which involves the farnesoid X receptor (FXR)/NGF/transient receptor potential vanilloid (TRPV)1 axis. ...The findings show an MMC-dependent and FXR-mediated pron …
In this study, we tested the hypothesis that BAs cause VH via mucosal mast cell (MMC)-to-nociceptor signaling, which involves the farnesoid …
Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells.
Liu Z, Gu Y, Chakarov S, Bleriot C, Kwok I, Chen X, Shin A, Huang W, Dress RJ, Dutertre CA, Schlitzer A, Chen J, Ng LG, Wang H, Liu Z, Su B, Ginhoux F. Liu Z, et al. Among authors: chen j, chen x. Cell. 2019 Sep 5;178(6):1509-1525.e19. doi: 10.1016/j.cell.2019.08.009. Cell. 2019. PMID: 31491389 Free article.
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