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A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models.
Tay AHM, Prieto-Díaz R, Neo S, Tong L, Chen X, Carannante V, Önfelt B, Hartman J, Haglund F, Majellaro M, Azuaje J, Garcia-Mera X, Brea JM, Loza MI, Jespers W, Gutierrez-de-Teran H, Sotelo E, Lundqvist A. Tay AHM, et al. Among authors: chen x. J Immunother Cancer. 2022 May;10(5):e004592. doi: 10.1136/jitc-2022-004592. J Immunother Cancer. 2022. PMID: 35580926 Free PMC article.
CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment.
Neo SY, Yang Y, Record J, Ma R, Chen X, Chen Z, Tobin NP, Blake E, Seitz C, Thomas R, Wagner AK, Andersson J, de Boniface J, Bergh J, Murray S, Alici E, Childs R, Johansson M, Westerberg LS, Haglund F, Hartman J, Lundqvist A. Neo SY, et al. Among authors: chen z, chen x. J Clin Invest. 2020 Mar 2;130(3):1185-1198. doi: 10.1172/JCI128895. J Clin Invest. 2020. PMID: 31770109 Free PMC article.
Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds.
Peuget S, Zhu J, Sanz G, Singh M, Gaetani M, Chen X, Shi Y, Saei AA, Visnes T, Lindström MS, Rihani A, Moyano-Galceran L, Carlson JW, Hjerpe E, Joneborg U, Lehti K, Hartman J, Helleday T, Zubarev R, Selivanova G. Peuget S, et al. Among authors: chen x. Cancer Res. 2020 Apr 1;80(7):1538-1550. doi: 10.1158/0008-5472.CAN-19-2069. Epub 2020 Feb 4. Cancer Res. 2020. PMID: 32019870
Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction.
Chen X, Sifakis EG, Robertson S, Neo SY, Jun SH, Tong L, Hui Min AT, Lövrot J, Hellgren R, Margolin S, Bergh J, Foukakis T, Lagergren J, Lundqvist A, Ma R, Hartman J. Chen X, et al. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2209856120. doi: 10.1073/pnas.2209856120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574653 Free PMC article.
Solid-phase capture and profiling of open chromatin by spatial ATAC.
Llorens-Bobadilla E, Zamboni M, Marklund M, Bhalla N, Chen X, Hartman J, Frisén J, Ståhl PL. Llorens-Bobadilla E, et al. Among authors: chen x. Nat Biotechnol. 2023 Aug;41(8):1085-1088. doi: 10.1038/s41587-022-01603-9. Epub 2023 Jan 5. Nat Biotechnol. 2023. PMID: 36604544 Free PMC article.
Renal cell carcinoma escapes NK cell-mediated immune surveillance through the downregulation of DNAM-1.
Tong L, Kremer V, Neo SY, Liu Y, Chen Y, Wagner AK, Yang Y, Chen Z, Seitz C, Tobin NP, Ligtenberg MA, Alici E, Chen X, Haglund F, Seliger B, Harmenberg U, Colón E, Plogell AS, Liu LL, Lundqvist A. Tong L, et al. Among authors: chen z, chen x, chen y. Cancer Commun (Lond). 2023 Jul;43(7):855-859. doi: 10.1002/cac2.12446. Epub 2023 Jun 14. Cancer Commun (Lond). 2023. PMID: 37314951 Free PMC article. No abstract available.
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