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Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes-Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans.
Wang H, Song X, Liao H, Wang P, Zhang Y, Che L, Zhang J, Zhou Y, Cigliano A, Ament C, Superville D, Ribback S, Reeves M, Pes GM, Liang B, Wu H, Evert M, Calvisi DF, Zeng Y, Chen X. Wang H, et al. Among authors: chen x. Hepatology. 2021 Jul;74(1):248-263. doi: 10.1002/hep.31692. Epub 2021 Jun 15. Hepatology. 2021. PMID: 33368437 Free PMC article.
TAZ is indispensable for c-MYC-induced hepatocarcinogenesis.
Wang H, Zhang S, Zhang Y, Jia J, Wang J, Liu X, Zhang J, Song X, Ribback S, Cigliano A, Evert M, Liang B, Wu H, Calvisi DF, Zeng Y, Chen X. Wang H, et al. Among authors: chen x. J Hepatol. 2022 Jan;76(1):123-134. doi: 10.1016/j.jhep.2021.08.021. Epub 2021 Aug 28. J Hepatol. 2022. PMID: 34464659 Free PMC article.
Therapeutic efficacy of FASN inhibition in preclinical models of HCC.
Wang H, Zhou Y, Xu H, Wang X, Zhang Y, Shang R, O'Farrell M, Roessler S, Sticht C, Stahl A, Evert M, Calvisi DF, Zeng Y, Chen X. Wang H, et al. Among authors: chen x. Hepatology. 2022 Oct;76(4):951-966. doi: 10.1002/hep.32359. Epub 2022 Feb 16. Hepatology. 2022. PMID: 35076948 Free PMC article.
Serum miRNAs as predictive and preventive biomarker for pre-clinical hepatocellular carcinoma.
Li L, Chen J, Chen X, Tang J, Guo H, Wang X, Qian J, Luo G, He F, Lu X, Ding Y, Yang Y, Huang W, Hou G, Lin X, Ouyang Q, Li H, Wang R, Jiang F, Pu R, Lu J, Jin M, Tan Y, Gonzalez FJ, Cao G, Wu M, Wen H, Wu T, Jin L, Chen L, Wang H. Li L, et al. Among authors: chen j, chen l, chen x. Cancer Lett. 2016 Apr 10;373(2):234-40. doi: 10.1016/j.canlet.2016.01.028. Epub 2016 Feb 2. Cancer Lett. 2016. PMID: 26850373 Free PMC article.
Hippo Cascade Controls Lineage Commitment of Liver Tumors in Mice and Humans.
Zhang S, Wang J, Wang H, Fan L, Fan B, Zeng B, Tao J, Li X, Che L, Cigliano A, Ribback S, Dombrowski F, Chen B, Cong W, Wei L, Calvisi DF, Chen X. Zhang S, et al. Among authors: chen b, chen x. Am J Pathol. 2018 Apr;188(4):995-1006. doi: 10.1016/j.ajpath.2017.12.017. Epub 2018 Jan 31. Am J Pathol. 2018. PMID: 29378174 Free PMC article.
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