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An analytical strategy to investigate Semen Strychni nephrotoxicity based on simultaneous HILIC-ESI-MS/MS detection of Semen Strychni alkaloids, tyrosine and tyramine in HEK 293t cell lysates.
Gu L, Hou P, Zhang R, Liu Z, Bi K, Chen X. Gu L, et al. Among authors: chen x. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 15;1033-1034:157-165. doi: 10.1016/j.jchromb.2016.08.021. Epub 2016 Aug 16. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27561182
Investigation of potential toxic components based on the identification of Genkwa Flos chemical constituents and their metabolites by high-performance liquid chromatography coupled with a Q Exactive high-resolution benchtop quadrupole Orbitrap mass spectrometer.
Wang Z, Chu Y, Zhang Y, Chen Y, Zhang J, Chen X. Wang Z, et al. Among authors: chen x, chen y. J Sep Sci. 2018 Aug;41(16):3328-3338. doi: 10.1002/jssc.201800424. Epub 2018 Jul 18. J Sep Sci. 2018. PMID: 29957847
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