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GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2.
Li ZW, Sun B, Gong T, Guo S, Zhang J, Wang J, Sugawara A, Jiang M, Yan J, Gurary A, Zheng X, Gao B, Xiao SY, Chen W, Ma C, Farrar C, Zhu C, Chan OTM, Xin C, Winnicki A, Winnicki J, Tang M, Park R, Winnicki M, Diener K, Wang Z, Liu Q, Chu CH, Arter ZL, Yue P, Alpert L, Hui GS, Fei P, Turkson J, Yang W, Wu G, Tao A, Ramos JW, Moisyadi S, Holcombe RF, Jia W, Birnbaumer L, Zhou X, Chu WM. Li ZW, et al. Among authors: chen w. Gastroenterology. 2019 Jun;156(8):2297-2312. doi: 10.1053/j.gastro.2019.02.040. Epub 2019 Mar 2. Gastroenterology. 2019. PMID: 30836096 Free PMC article.
Distinctly altered gut microbiota in the progression of liver disease.
Xie G, Wang X, Liu P, Wei R, Chen W, Rajani C, Hernandez BY, Alegado R, Dong B, Li D, Jia W. Xie G, et al. Among authors: chen w. Oncotarget. 2016 Apr 12;7(15):19355-66. doi: 10.18632/oncotarget.8466. Oncotarget. 2016. PMID: 27036035 Free PMC article.
Dysregulated hepatic bile acids collaboratively promote liver carcinogenesis.
Xie G, Wang X, Huang F, Zhao A, Chen W, Yan J, Zhang Y, Lei S, Ge K, Zheng X, Liu J, Su M, Liu P, Jia W. Xie G, et al. Among authors: chen w. Int J Cancer. 2016 Oct 15;139(8):1764-75. doi: 10.1002/ijc.30219. Epub 2016 Jun 17. Int J Cancer. 2016. PMID: 27273788 Free PMC article.
The ratio of dihomo-γ-linolenic acid to deoxycholic acid species is a potential biomarker for the metabolic abnormalities in obesity.
Lei S, Huang F, Zhao A, Chen T, Chen W, Xie G, Zheng X, Zhang Y, Yu H, Zhang P, Rajani C, Bao Y, Jia W, Jia W. Lei S, et al. Among authors: chen t, chen w. FASEB J. 2017 Sep;31(9):3904-3912. doi: 10.1096/fj.201700055R. Epub 2017 May 10. FASEB J. 2017. PMID: 28490483 Free PMC article.
Thus, the DGLA:DCAS ratio may be a promising biomarker for metabolic abnormalities in obesity.-Lei, S., Huang, F., Zhao, A., Chen, T., Chen, W., Xie, G., Zheng, X., Zhang, Y., Yu, H., Zhang, P., Rajani, C., Bao, Y., Jia, W., Jia, W. ...
Thus, the DGLA:DCAS ratio may be a promising biomarker for metabolic abnormalities in obesity.-Lei, S., Huang, F., Zhao, A., Chen, T. …
Bile Acid-Microbiome Interaction Promotes Gastric Carcinogenesis.
Wang S, Kuang J, Zhang H, Chen W, Zheng X, Wang J, Huang F, Ge K, Li M, Zhao M, Rajani C, Zhu J, Zhao A, Jia W. Wang S, et al. Among authors: chen w. Adv Sci (Weinh). 2022 May;9(16):e2200263. doi: 10.1002/advs.202200263. Epub 2022 Mar 14. Adv Sci (Weinh). 2022. PMID: 35285172 Free PMC article.
A distinct glucose metabolism signature of acute myeloid leukemia with prognostic value.
Chen WL, Wang JH, Zhao AH, Xu X, Wang YH, Chen TL, Li JM, Mi JQ, Zhu YM, Liu YF, Wang YY, Jin J, Huang H, Wu DP, Li Y, Yan XJ, Yan JS, Li JY, Wang S, Huang XJ, Wang BS, Chen Z, Chen SJ, Jia W. Chen WL, et al. Among authors: chen z, chen tl, chen sj. Blood. 2014 Sep 4;124(10):1645-54. doi: 10.1182/blood-2014-02-554204. Epub 2014 Jul 8. Blood. 2014. PMID: 25006128 Free PMC article.
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