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Apatinib Combined with Local Irradiation Leads to Systemic Tumor Control via Reversal of Immunosuppressive Tumor Microenvironment in Lung Cancer.
Liang LJ, Hu CX, Wen YX, Geng XW, Chen T, Gu GQ, Wang L, Xia YY, Liu Y, Fei JY, Dong J, Zhao FH, Ahongjiang Y, Hui KY, Jiang XD. Liang LJ, et al. Among authors: chen t. Cancer Res Treat. 2020 Apr;52(2):406-418. doi: 10.4143/crt.2019.296. Epub 2019 Sep 3. Cancer Res Treat. 2020. PMID: 31476848 Free PMC article.
Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells.
Liang L, Hui K, Hu C, Wen Y, Yang S, Zhu P, Wang L, Xia Y, Qiao Y, Sun W, Fei J, Chen T, Zhao F, Yang B, Jiang X. Liang L, et al. Among authors: chen t. J Exp Clin Cancer Res. 2019 Feb 12;38(1):71. doi: 10.1186/s13046-019-1093-3. J Exp Clin Cancer Res. 2019. PMID: 30755242 Free PMC article.
Safety and efficacy of PD-1 blockade-activated multiple antigen-specific cellular therapy alone or in combination with apatinib in patients with advanced solid tumors: a pooled analysis of two prospective trials.
Liang L, Wen Y, Hu R, Wang L, Xia Y, Hu C, Qiao Y, Geng X, Chen T, Fei J, Hui K, Jiang X. Liang L, et al. Among authors: chen t. Cancer Immunol Immunother. 2019 Sep;68(9):1467-1477. doi: 10.1007/s00262-019-02375-z. Epub 2019 Aug 27. Cancer Immunol Immunother. 2019. PMID: 31451841 Free PMC article. Clinical Trial.
Targeting HER2 Aberrations in Non-Small Cell Lung Cancer with Osimertinib.
Liu S, Li S, Hai J, Wang X, Chen T, Quinn MM, Gao P, Zhang Y, Ji H, Cross DAE, Wong KK. Liu S, et al. Among authors: chen t. Clin Cancer Res. 2018 Jun 1;24(11):2594-2604. doi: 10.1158/1078-0432.CCR-17-1875. Epub 2018 Jan 3. Clin Cancer Res. 2018. PMID: 29298799 Free PMC article.
In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma.
Li F, Huang Q, Luster TA, Hu H, Zhang H, Ng WL, Khodadadi-Jamayran A, Wang W, Chen T, Deng J, Ranieri M, Fang Z, Pyon V, Dowling CM, Bagdatlioglu E, Almonte C, Labbe K, Silver H, Rabin AR, Jani K, Tsirigos A, Papagiannakopoulos T, Hammerman PS, Velcheti V, Freeman GJ, Qi J, Miller G, Wong KK. Li F, et al. Among authors: chen t. Cancer Discov. 2020 Feb;10(2):270-287. doi: 10.1158/2159-8290.CD-19-0780. Epub 2019 Nov 19. Cancer Discov. 2020. PMID: 31744829 Free PMC article.
Use of Ex Vivo Patient-Derived Tumor Organotypic Spheroids to Identify Combination Therapies for HER2 Mutant Non-Small Cell Lung Cancer.
Ivanova E, Kuraguchi M, Xu M, Portell AJ, Taus L, Diala I, Lalani AS, Choi J, Chambers ES, Li S, Liu S, Chen T, Barbie TU, Oxnard GR, Haworth JJ, Wong KK, Dahlberg SE, Aref AA, Barbie DA, Bahcall M, Paweletz CP, Jänne PA. Ivanova E, et al. Among authors: chen t. Clin Cancer Res. 2020 May 15;26(10):2393-2403. doi: 10.1158/1078-0432.CCR-19-1844. Epub 2020 Feb 7. Clin Cancer Res. 2020. PMID: 32034078 Free PMC article.
Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non-Small Cell Lung Cancer.
Li F, Ng WL, Luster TA, Hu H, Sviderskiy VO, Dowling CM, Hollinshead KER, Zouitine P, Zhang H, Huang Q, Ranieri M, Wang W, Fang Z, Chen T, Deng J, Zhao K, So HC, Khodadadi-Jamayran A, Xu M, Karatza A, Pyon V, Li S, Pan Y, Labbe K, Almonte C, Poirier JT, Miller G, Possemato R, Qi J, Wong KK. Li F, et al. Among authors: chen t. Cancer Res. 2020 Sep 1;80(17):3556-3567. doi: 10.1158/0008-5472.CAN-19-3782. Epub 2020 Jul 9. Cancer Res. 2020. PMID: 32646968 Free PMC article.
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