Chen S - Search Results

1

Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations.

Khor CC, Winter S, Sutiman N, Mürdter TE, Chen S, Lim JSL, Li Z, Li J, Sim KS, Ganchev B, Eccles D, Eccles B, Tapper W, Zgheib NK, Tfayli A, Ng RCH, Yap YS, Lim E, Wong M, Wong NS, Ang PCS, Dent R, Tremmel R, Klein K, Schaeffeler E, Zhou Y, Lauschke VM, Eichelbaum M, Schwab M, Brauch HB, Chowbay B, Schroth W. Khor CC, et al. Among authors: chen s. Clin Pharmacol Ther. 2023 Mar;113(3):712-723. doi: 10.1002/cpt.2846. Epub 2023 Jan 31. Clin Pharmacol Ther. 2023. PMID: 36629403

2

Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.

Chen S, Sutiman N, Zhang CZ, Yu Y, Lam S, Khor CC, Chowbay B. Chen S, et al. Drug Metab Rev. 2016 Nov;48(4):502-540. doi: 10.1080/03602532.2016.1226896. Drug Metab Rev. 2016. PMID: 27546072 Review.

3

Pharmacogenetics of drug transporters in modulating imatinib disposition and treatment outcomes in chronic myeloid leukemia & gastrointestinal stromal tumor patients.

Chen S, Sutiman N, Chowbay B. Chen S, et al. Pharmacogenomics. 2016 Nov;17(17):1941-1955. doi: 10.2217/pgs-2016-0124. Epub 2016 Nov 2. Pharmacogenomics. 2016. PMID: 27804783

4

Predictive role of NUDT15 variants on thiopurine-induced myelotoxicity in Asian inflammatory bowel disease patients.

Sutiman N, Chen S, Ling KL, Chuah SW, Leong WF, Nadiger V, Tjai M, Choon Kong CS, Schwender BJ, Chan W, Shim HH, Lim WC, Khor CC, Cheung YB, Chowbay B. Sutiman N, et al. Among authors: chen s. Pharmacogenomics. 2018 Jan;19(1):31-43. doi: 10.2217/pgs-2017-0147. Epub 2017 Dec 6. Pharmacogenomics. 2018. PMID: 29210335 Free PMC article.

5

An intronic FTO variant rs16952570 confers protection against thiopurine-induced myelotoxicities in multiethnic Asian IBD patients.

Chen S, Tan WZ, Sutiman N, Lim C, Lee SS, Leong WF, Tjai M, Wang C, Kong CSC, Chuah SW, Schwender BJ, Chan W, Shim HH, Lim WC, Khor CC, Ling KL, Chowbay B. Chen S, et al. Pharmacogenomics J. 2020 Jun;20(3):505-515. doi: 10.1038/s41397-019-0126-9. Epub 2019 Dec 9. Pharmacogenomics J. 2020. PMID: 31813937

6

Obesity Alters Endoxifen Plasma Levels in Young Breast Cancer Patients: A Pharmacometric Simulation Approach.

Mueller-Schoell A, Klopp-Schulze L, Schroth W, Mürdter T, Michelet R, Brauch H, Huisinga W, Joerger M, Neven P, Koolen SLW, Mathijssen RHJ, Copson E, Eccles D, Chen S, Chowbay B, Tfayli A, Zgheib NK, Schwab M, Kloft C. Mueller-Schoell A, et al. Among authors: chen s. Clin Pharmacol Ther. 2020 Sep;108(3):661-670. doi: 10.1002/cpt.1960. Epub 2020 Jul 23. Clin Pharmacol Ther. 2020. PMID: 32578187

7

Pharmacokinetics of oral versus intravenous ibuprofen for closure of patent ductus arteriosus: A pilot randomised controlled study.

Edison PE, Chen S, Yeo CL, Allen JC Jr, Poon WB, Baral VR, Chowbay B. Edison PE, et al. Among authors: chen s. J Paediatr Child Health. 2022 Mar;58(3):397-403. doi: 10.1111/jpc.15720. Epub 2021 Sep 3. J Paediatr Child Health. 2022. PMID: 34477275 Clinical Trial.

8

A phase 1b study of OXIRI in pancreatic adenocarcinoma patients and its immunomodulatory effects.

Ng M, Chen S, Ong WS, Balachander A, Seet A, Yeong J, Sutiman N, Lim TKH, Lee B, Guo YA, Leong WF, Lee SS, Lam J, Choo SP, Skanderup AJ, Biswas SK, Tai D, Chowbay B. Ng M, et al. Among authors: chen s. Int J Cancer. 2022 Aug 1;151(3):435-449. doi: 10.1002/ijc.34021. Epub 2022 May 6. Int J Cancer. 2022. PMID: 35415893 Free article. Clinical Trial.

9

Pharmacokinetic and pharmacogenomic considerations in managing use of nirmatrelvir-ritonavir and molnupiravir and dermatological treatments.

Chen S, Leong WF, Lee SS, Chowbay B. Chen S, et al. Ann Acad Med Singap. 2022 Dec;51(12):752-754. doi: 10.47102/annals-acadmedsg.2022430. Ann Acad Med Singap. 2022. PMID: 36592143 Free article. No abstract available.

10

Automated warfarin dose prediction for Asian, American, and Caucasian populations using a deep neural network.

Jahmunah V, Chen S, Oh SL, Acharya UR, Chowbay B. Jahmunah V, et al. Among authors: chen s. Comput Biol Med. 2023 Feb;153:106548. doi: 10.1016/j.compbiomed.2023.106548. Epub 2023 Jan 13. Comput Biol Med. 2023. PMID: 36652867

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