Chen S - Search Results

1

A non-canonical cGAS-STING-PERK pathway facilitates the translational program critical for senescence and organ fibrosis.

Zhang D, Liu Y, Zhu Y, Zhang Q, Guan H, Liu S, Chen S, Mei C, Chen C, Liao Z, Xi Y, Ouyang S, Feng XH, Liang T, Shen L, Xu P. Zhang D, et al. Among authors: chen s, chen c. Nat Cell Biol. 2022 May;24(5):766-782. doi: 10.1038/s41556-022-00894-z. Epub 2022 May 2. Nat Cell Biol. 2022. PMID: 35501370

2

Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade.

Zhang Q, Meng F, Chen S, Plouffe SW, Wu S, Liu S, Li X, Zhou R, Wang J, Zhao B, Liu J, Qin J, Zou J, Feng XH, Guan KL, Xu P. Zhang Q, et al. Among authors: chen s. Nat Cell Biol. 2017 Apr;19(4):362-374. doi: 10.1038/ncb3496. Epub 2017 Mar 27. Nat Cell Biol. 2017. PMID: 28346439 Free PMC article.

3

Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses.

Liu S, Chen S, Li X, Wu S, Zhang Q, Jin Q, Hu L, Zhou R, Yu Z, Meng F, Wang S, Huang Y, Ye S, Shen L, Xia Z, Zou J, Feng XH, Xu P. Liu S, et al. Among authors: chen s. Cell Host Microbe. 2017 Jun 14;21(6):754-768.e5. doi: 10.1016/j.chom.2017.05.010. Cell Host Microbe. 2017. PMID: 28618271 Free article.

4

TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology.

Chen S, Liu S, Wang J, Wu Q, Wang A, Guan H, Zhang Q, Zhang D, Wang X, Song H, Qin J, Zou J, Jiang Z, Ouyang S, Feng XH, Liang T, Xu P. Chen S, et al. Mol Cell. 2020 Dec 3;80(5):810-827.e7. doi: 10.1016/j.molcel.2020.10.018. Epub 2020 Nov 9. Mol Cell. 2020. PMID: 33171123 Free article.

5

Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity.

Meng F, Yu Z, Zhang D, Chen S, Guan H, Zhou R, Wu Q, Zhang Q, Liu S, Venkat Ramani MK, Yang B, Ba XQ, Zhang J, Huang J, Bai X, Qin J, Feng XH, Ouyang S, Zhang YJ, Liang T, Xu P. Meng F, et al. Among authors: chen s. Mol Cell. 2021 Oct 21;81(20):4147-4164.e7. doi: 10.1016/j.molcel.2021.07.040. Epub 2021 Aug 27. Mol Cell. 2021. PMID: 34453890 Free article.

6

AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity.

Zhang Q, Liu S, Zhang CS, Wu Q, Yu X, Zhou R, Meng F, Wang A, Zhang F, Chen S, Wang X, Li L, Huang J, Huang YW, Zou J, Qin J, Liang T, Feng XH, Lin SC, Xu P. Zhang Q, et al. Among authors: chen s. Mol Cell. 2022 Dec 1;82(23):4519-4536.e7. doi: 10.1016/j.molcel.2022.10.026. Epub 2022 Nov 15. Mol Cell. 2022. PMID: 36384137 Free article.

7

The TRIM21-FOXD1-BCL-2 axis underlies hyperglycaemic cell death and diabetic tissue damage.

Cheng W, Cai C, Xu Y, Xiao X, Shi T, Liao Y, Wang X, Chen S, Zhou M, Liao Z. Cheng W, et al. Among authors: chen s. Cell Death Dis. 2023 Dec 13;14(12):825. doi: 10.1038/s41419-023-06355-1. Cell Death Dis. 2023. PMID: 38092733 Free PMC article.

8

Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders.

Wang A, Chen C, Mei C, Liu S, Xiang C, Fang W, Zhang F, Xu Y, Chen S, Zhang Q, Bai X, Lin A, Neculai D, Xia B, Ye C, Zou J, Liang T, Feng XH, Li X, Shen C, Xu P. Wang A, et al. Among authors: chen c, chen s. Nat Cell Biol. 2024 Feb;26(2):219-234. doi: 10.1038/s41556-023-01339-x. Epub 2024 Jan 22. Nat Cell Biol. 2024. PMID: 38253667

9

Unleashing a safe and potent pro-senescence anti-tumor strategy.

Chen S, Sun B, Dong Z. Chen S, et al. Cancer Cell. 2024 Apr 8;42(4):504-507. doi: 10.1016/j.ccell.2024.02.003. Epub 2024 Feb 29. Cancer Cell. 2024. PMID: 38428411

10

Stage-specific requirement of kinase PDK1 for NK cells development and activation.

He J, Wang Y, Liu T, Liu G, Chen S, Li Q, Quan Y, Yang H, Feng J, Wang S, Yang M, Dong Z. He J, et al. Among authors: chen s. Cell Death Differ. 2019 Oct;26(10):1918-1928. doi: 10.1038/s41418-018-0263-8. Epub 2019 Jan 8. Cell Death Differ. 2019. PMID: 30622306 Free PMC article.

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