Chen S - Search Results

1

High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells.

Chen JS, Chow RD, Song E, Mao T, Israelow B, Kamath K, Bozekowski J, Haynes WA, Filler RB, Menasche BL, Wei J, Alfajaro MM, Song W, Peng L, Carter L, Weinstein JS, Gowthaman U, Chen S, Craft J, Shon JC, Iwasaki A, Wilen CB, Eisenbarth SC. Chen JS, et al. Among authors: chen s. Sci Immunol. 2022 Feb 4;7(68):eabl5652. doi: 10.1126/sciimmunol.abl5652. Epub 2022 Feb 4. Sci Immunol. 2022. PMID: 34914544 Free PMC article.

2

Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening.

Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S. Wang G, et al. Among authors: chen s. Sci Adv. 2018 Feb 28;4(2):eaao5508. doi: 10.1126/sciadv.aao5508. eCollection 2018 Feb. Sci Adv. 2018. PMID: 29503867 Free PMC article.

3

Cancer CRISPR Screens In Vivo.

Chow RD, Chen S. Chow RD, et al. Among authors: chen s. Trends Cancer. 2018 May;4(5):349-358. doi: 10.1016/j.trecan.2018.03.002. Epub 2018 Mar 30. Trends Cancer. 2018. PMID: 29709259 Free PMC article. Review.

4

Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion.

Chow RD, Kim HR, Chen S. Chow RD, et al. Among authors: chen s. Nat Commun. 2018 May 15;9(1):1903. doi: 10.1038/s41467-018-04158-z. Nat Commun. 2018. PMID: 29765043 Free PMC article.

5

Sno-derived RNAs are prevalent molecular markers of cancer immunity.

Chow RD, Chen S. Chow RD, et al. Among authors: chen s. Oncogene. 2018 Dec;37(50):6442-6462. doi: 10.1038/s41388-018-0420-z. Epub 2018 Aug 2. Oncogene. 2018. PMID: 30072739 Free PMC article.

6

Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo.

Codina A, Renauer PA, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, Bosenberg M, Rinehart J, Fan R, Chen S. Codina A, et al. Among authors: chen s. Cell Syst. 2019 Feb 27;8(2):136-151.e7. doi: 10.1016/j.cels.2019.01.004. Epub 2019 Feb 20. Cell Syst. 2019. PMID: 30797773 Free PMC article.

7

In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens.

Chow RD, Wang G, Ye L, Codina A, Kim HR, Shen L, Dong MB, Errami Y, Chen S. Chow RD, et al. Among authors: chen s. Nat Methods. 2019 May;16(5):405-408. doi: 10.1038/s41592-019-0371-5. Epub 2019 Apr 8. Nat Methods. 2019. PMID: 30962622 Free PMC article.

8

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells.

Dong MB, Wang G, Chow RD, Ye L, Zhu L, Dai X, Park JJ, Kim HR, Errami Y, Guzman CD, Zhou X, Chen KY, Renauer PA, Du Y, Shen J, Lam SZ, Zhou JJ, Lannin DR, Herbst RS, Chen S. Dong MB, et al. Among authors: chen ky, chen s. Cell. 2019 Aug 22;178(5):1189-1204.e23. doi: 10.1016/j.cell.2019.07.044. Cell. 2019. PMID: 31442407 Free PMC article.

9

In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma.

Ye L, Park JJ, Dong MB, Yang Q, Chow RD, Peng L, Du Y, Guo J, Dai X, Wang G, Errami Y, Chen S. Ye L, et al. Among authors: chen s. Nat Biotechnol. 2019 Nov;37(11):1302-1313. doi: 10.1038/s41587-019-0246-4. Epub 2019 Sep 23. Nat Biotechnol. 2019. PMID: 31548728 Free PMC article.

10

Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity.

Wang G, Chow RD, Bai Z, Zhu L, Errami Y, Dai X, Dong MB, Ye L, Zhang X, Renauer PA, Park JJ, Shen L, Ye H, Fuchs CS, Chen S. Wang G, et al. Among authors: chen s. Nat Immunol. 2019 Nov;20(11):1494-1505. doi: 10.1038/s41590-019-0500-4. Epub 2019 Oct 14. Nat Immunol. 2019. PMID: 31611701 Free PMC article.

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