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Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation.
Dagvadorj J, Mikulska-Ruminska K, Tumurkhuu G, Ratsimandresy RA, Carriere J, Andres AM, Marek-Iannucci S, Song Y, Chen S, Lane M, Dorfleutner A, Gottlieb RA, Stehlik C, Cassel S, Sutterwala FS, Bahar I, Crother TR, Arditi M. Dagvadorj J, et al. Among authors: chen s. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2015632118. doi: 10.1073/pnas.2015632118. Proc Natl Acad Sci U S A. 2021. PMID: 33361152 Free PMC article.
Emerging role of IL-17 in atherosclerosis.
Chen S, Crother TR, Arditi M. Chen S, et al. J Innate Immun. 2010;2(4):325-33. doi: 10.1159/000314626. Epub 2010 May 7. J Innate Immun. 2010. PMID: 20505315 Free PMC article. Review.
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, Underhill DM, Town T, Arditi M. Shimada K, et al. Among authors: chen s. Immunity. 2012 Mar 23;36(3):401-14. doi: 10.1016/j.immuni.2012.01.009. Epub 2012 Feb 16. Immunity. 2012. PMID: 22342844 Free PMC article.
IL-1 Signaling Is Critically Required in Stromal Cells in Kawasaki Disease Vasculitis Mouse Model: Role of Both IL-1α and IL-1β.
Lee Y, Wakita D, Dagvadorj J, Shimada K, Chen S, Huang G, Lehman TJ, Fishbein MC, Hoffman HM, Crother TR, Arditi M. Lee Y, et al. Among authors: chen s. Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2605-16. doi: 10.1161/ATVBAHA.115.306475. Epub 2015 Oct 29. Arterioscler Thromb Vasc Biol. 2015. PMID: 26515418 Free PMC article.
Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease-Associated Abdominal Aortic Aneurysm.
Wakita D, Kurashima Y, Crother TR, Noval Rivas M, Lee Y, Chen S, Fury W, Bai Y, Wagner S, Li D, Lehman T, Fishbein MC, Hoffman HM, Shah PK, Shimada K, Arditi M. Wakita D, et al. Among authors: chen s. Arterioscler Thromb Vasc Biol. 2016 May;36(5):886-97. doi: 10.1161/ATVBAHA.115.307072. Epub 2016 Mar 3. Arterioscler Thromb Vasc Biol. 2016. PMID: 26941015 Free PMC article.
Autophagy Limits Inflammasome During Chlamydia pneumoniae Infection.
Crother TR, Porritt RA, Dagvadorj J, Tumurkhuu G, Slepenkin AV, Peterson EM, Chen S, Shimada K, Arditi M. Crother TR, et al. Among authors: chen s. Front Immunol. 2019 Apr 12;10:754. doi: 10.3389/fimmu.2019.00754. eCollection 2019. Front Immunol. 2019. PMID: 31031755 Free PMC article.
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