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The promise of omics-based approaches to cancer prevention.
Meerzaman D, Dunn BK, Lee M, Chen Q, Yan C, Ross S. Meerzaman D, et al. Among authors: chen q. Semin Oncol. 2016 Feb;43(1):36-48. doi: 10.1053/j.seminoncol.2015.09.004. Epub 2015 Sep 8. Semin Oncol. 2016. PMID: 26970123 Review.
The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells.
Gegonne A, Tai X, Zhang J, Wu G, Zhu J, Yoshimoto A, Hanson J, Cultraro C, Chen QR, Guinter T, Yang Z, Hathcock K, Singer A, Rodriguez-Canales J, Tessarollo L, Mackem S, Meerzaman D, Buetow K, Singer DS. Gegonne A, et al. Mol Cell Biol. 2012 May;32(10):1984-97. doi: 10.1128/MCB.06305-11. Epub 2012 Mar 12. Mol Cell Biol. 2012. PMID: 22411629 Free PMC article.
Genome-wide transcriptional sequencing identifies novel mutations in metabolic genes in human hepatocellular carcinoma.
Meerzaman DM, Yan C, Chen QR, Edmonson MN, Schaefer CF, Clifford RJ, Dunn BK, Dong L, Finney RP, Cultraro CM, Hu Y, Yang Z, Nguyen CV, Kelley JM, Cai S, Zhang H, Zhang J, Wilson R, Messmer L, Chung YH, Kim JA, Park NH, Lyu MS, Song IH, Komatsoulis G, Buetow KH. Meerzaman DM, et al. Cancer Genomics Proteomics. 2014 Jan-Feb;11(1):1-12. Cancer Genomics Proteomics. 2014. PMID: 24633315
Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.
Walz AL, Ooms A, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Bowlby R, Brooks D, Ma Y, Mungall AJ, Moore RA, Schein J, Marra MA, Huff V, Dome JS, Chi YY, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Jafari N, Ross N, Gastier-Foster JM, Perlman EJ. Walz AL, et al. Cancer Cell. 2015 Feb 9;27(2):286-97. doi: 10.1016/j.ccell.2015.01.003. Cancer Cell. 2015. PMID: 25670082 Free PMC article.
Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection.
Ewing AD, Houlahan KE, Hu Y, Ellrott K, Caloian C, Yamaguchi TN, Bare JC, P'ng C, Waggott D, Sabelnykova VY; ICGC-TCGA DREAM Somatic Mutation Calling Challenge participants; Kellen MR, Norman TC, Haussler D, Friend SH, Stolovitzky G, Margolin AA, Stuart JM, Boutros PC. Ewing AD, et al. Nat Methods. 2015 Jul;12(7):623-30. doi: 10.1038/nmeth.3407. Epub 2015 May 18. Nat Methods. 2015. PMID: 25984700 Free PMC article.
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