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Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
Bollu LR, Bommi PV, Monsen PJ, Zhai L, Lauing KL, Bell A, Kim M, Ladomersky E, Yang X, Platanias LC, Matei DE, Bonini MG, Munshi HG, Hashizume R, Wu JD, Zhang B, James CD, Chen P, Kocherginsky M, Horbinski C, Cameron MD, Grigorescu AA, Yamini B, Lukas RV, Schiltz GE, Wainwright DA. Bollu LR, et al. Among authors: chen p. J Med Chem. 2022 Dec 8;65(23):15642-15662. doi: 10.1021/acs.jmedchem.2c00771. Epub 2022 Nov 21. J Med Chem. 2022. PMID: 36410047 Free PMC article.
Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma.
Zhai L, Bell A, Ladomersky E, Lauing KL, Bollu L, Nguyen B, Genet M, Kim M, Chen P, Mi X, Wu JD, Schipma MJ, Wray B, Griffiths J, Unwin RD, Clark SJ, Acharya R, Bao R, Horbinski C, Lukas RV, Schiltz GE, Wainwright DA. Zhai L, et al. Among authors: chen p. Clin Cancer Res. 2021 Dec 1;27(23):6514-6528. doi: 10.1158/1078-0432.CCR-21-1392. Epub 2021 Sep 3. Clin Cancer Res. 2021. PMID: 34479957 Free PMC article.
CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease.
Najem H, Marisetty A, Horbinski C, Long J, Huse JT, Glitza Oliva IC, Ferguson SD, Kumthekar PU, Wainwright DA, Chen P, Lesniak MS, Burks JK, Heimberger AB. Najem H, et al. Among authors: chen p. Front Immunol. 2021 Oct 8;12:745893. doi: 10.3389/fimmu.2021.745893. eCollection 2021. Front Immunol. 2021. PMID: 34691054 Free PMC article.
Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma.
Xuan W, Hsu WH, Khan F, Dunterman M, Pang L, Wainwright DA, Ahmed AU, Heimberger AB, Lesniak MS, Chen P. Xuan W, et al. Among authors: chen p. Cancer Immunol Res. 2022 Jun 3;10(6):770-784. doi: 10.1158/2326-6066.CIR-21-0559. Cancer Immunol Res. 2022. PMID: 35413115 Free PMC article.
LDHA-regulated tumor-macrophage symbiosis promotes glioblastoma progression.
Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Rowe RG, Wainwright D, McCortney K, Billingham L, Miska J, Horbinski C, Lesniak M, Chen P. Khan F, et al. Among authors: chen p. Res Sq [Preprint]. 2023 Oct 5:rs.3.rs-3401154. doi: 10.21203/rs.3.rs-3401154/v1. Res Sq. 2023. PMID: 37886538 Free PMC article. Updated. Preprint.
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