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Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants.
Tian S, Xiong X, Zeng J, Wang S, Tremblay BJ, Chen P, Chen B, Liu M, Chen P, Sheng K, Zeve D, Qi W, Breault DT, Rodríguez C, Gerhard R, Jin R, Doxey AC, Dong M. Tian S, et al. Among authors: chen p, chen b. Nat Commun. 2022 Nov 9;13(1):6786. doi: 10.1038/s41467-022-33964-9. Nat Commun. 2022. PMID: 36351897 Free PMC article.
Structure of the full-length Clostridium difficile toxin B.
Chen P, Lam KH, Liu Z, Mindlin FA, Chen B, Gutierrez CB, Huang L, Zhang Y, Hamza T, Feng H, Matsui T, Bowen ME, Perry K, Jin R. Chen P, et al. Among authors: chen b. Nat Struct Mol Biol. 2019 Aug;26(8):712-719. doi: 10.1038/s41594-019-0268-0. Epub 2019 Jul 15. Nat Struct Mol Biol. 2019. PMID: 31308519 Free PMC article.
Structure and conformational dynamics of Clostridioides difficile toxin A.
Chen B, Basak S, Chen P, Zhang C, Perry K, Tian S, Yu C, Dong M, Huang L, Bowen ME, Jin R. Chen B, et al. Among authors: chen p. Life Sci Alliance. 2022 Mar 15;5(6):e202201383. doi: 10.26508/lsa.202201383. Print 2022 Jun. Life Sci Alliance. 2022. PMID: 35292538 Free PMC article.
Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth.
He A, Tian S, Kopper O, Horan DJ, Chen P, Bronson RT, Sheng R, Wu H, Sui L, Zhou K, Tao L, Wu Q, Huang Y, Shen Z, Han S, Chen X, Chen H, He X, Robling AG, Jin R, Clevers H, Xiang D, Li Z, Dong M. He A, et al. Among authors: chen p, chen x, chen h. PLoS Biol. 2023 Nov 9;21(11):e3002353. doi: 10.1371/journal.pbio.3002353. eCollection 2023 Nov. PLoS Biol. 2023. PMID: 37943878 Free PMC article.
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