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Manganese inhibits NMDA receptor channel function: implications to psychiatric and cognitive effects.
Guilarte TR, Chen MK. Guilarte TR, et al. Among authors: chen mk. Neurotoxicology. 2007 Nov;28(6):1147-52. doi: 10.1016/j.neuro.2007.06.005. Epub 2007 Jun 26. Neurotoxicology. 2007. PMID: 17662456 Free PMC article.
We also show that Mn(2+) is a NMDA receptor channel blocker since its inhibition of [(3)H]-MK-801 binding to the NMDA receptor channel is competitive in nature. That is, Mn(2+) significantly increased the affinity constant (K(d)) with no significant effect on the maximal n …
We also show that Mn(2+) is a NMDA receptor channel blocker since its inhibition of [(3)H]-MK-801 binding to the NMDA receptor channe …
VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease.
Chen MK, Kuwabara H, Zhou Y, Adams RJ, Brasić JR, McGlothan JL, Verina T, Burton NC, Alexander M, Kumar A, Wong DF, Guilarte TR. Chen MK, et al. J Neurochem. 2008 Apr;105(1):78-90. doi: 10.1111/j.1471-4159.2007.05108.x. Epub 2007 Nov 5. J Neurochem. 2008. PMID: 17988241 Free PMC article.
630 results