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Regulation of OATP1B1 Function by Tyrosine Kinase-mediated Phosphorylation.
Hayden ER, Chen M, Pasquariello KZ, Gibson AA, Petti JJ, Shen S, Qu J, Ong SS, Chen T, Jin Y, Uddin ME, Huang KM, Paz A, Sparreboom A, Hu S, Sprowl JA. Hayden ER, et al. Among authors: chen m, chen t. Clin Cancer Res. 2021 Aug 1;27(15):4301-4310. doi: 10.1158/1078-0432.CCR-21-0023. Epub 2021 Mar 4. Clin Cancer Res. 2021. PMID: 33664059 Free PMC article.
OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.
Leblanc AF, Sprowl JA, Alberti P, Chiorazzi A, Arnold WD, Gibson AA, Hong KW, Pioso MS, Chen M, Huang KM, Chodisetty V, Costa O, Florea T, de Bruijn P, Mathijssen RH, Reinbolt RE, Lustberg MB, Sucheston-Campbell LE, Cavaletti G, Sparreboom A, Hu S. Leblanc AF, et al. Among authors: chen m. J Clin Invest. 2018 Feb 1;128(2):816-825. doi: 10.1172/JCI96160. Epub 2018 Jan 16. J Clin Invest. 2018. PMID: 29337310 Free PMC article.
Murine Pharmacokinetic Studies.
Leblanc AF, Huang KM, Uddin ME, Anderson JT, Chen M, Hu S. Leblanc AF, et al. Among authors: chen m. Bio Protoc. 2018 Oct 20;8(20):e3056. doi: 10.21769/BioProtoc.3056. Bio Protoc. 2018. PMID: 31106235 Free PMC article.
Role of Oatp2b1 in Drug Absorption and Drug-Drug Interactions.
Chen M, Hu S, Li Y, Gibson AA, Fu Q, Baker SD, Sparreboom A. Chen M, et al. Drug Metab Dispos. 2020 May;48(5):419-425. doi: 10.1124/dmd.119.090316. Epub 2020 Feb 29. Drug Metab Dispos. 2020. PMID: 32114507 Free PMC article.
Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice.
Huang KM, Leblanc AF, Uddin ME, Kim JY, Chen M, Eisenmann ED, Gibson AA, Li Y, Hong KW, DiGiacomo D, Xia SH, Alberti P, Chiorazzi A, Housley SN, Cope TC, Sprowl JA, Wang J, Loprinzi CL, Noonan A, Lustberg MB, Cavaletti G, Pabla N, Hu S, Sparreboom A. Huang KM, et al. Among authors: chen m. J Clin Invest. 2020 Sep 1;130(9):4601-4606. doi: 10.1172/JCI136796. J Clin Invest. 2020. PMID: 32484793 Free PMC article.
Androgen receptor signalling impairs docetaxel efficacy in castration-resistant prostate cancer.
Mout L, Moll JM, Chen M, de Morrée ES, de Ridder CMA, Gibson A, Stuurman D, Aghai A, Erkens-Schulze S, Mathijssen RHJ, Sparreboom A, de Wit R, Lolkema MP, van Weerden WM. Mout L, et al. Among authors: chen m. Br J Cancer. 2020 Dec;123(12):1715-1719. doi: 10.1038/s41416-020-01105-y. Epub 2020 Sep 29. Br J Cancer. 2020. PMID: 32989230 Free PMC article.
Targeting a xenobiotic transporter to ameliorate vincristine-induced sensory neuropathy.
Li Y, Drabison T, Nepal M, Ho RH, Leblanc AF, Gibson AA, Jin Y, Yang W, Huang KM, Uddin ME, Chen M, DiGiacomo DF, Chen X, Razzaq S, Tonniges JR, McTigue DM, Mims AS, Lustberg MB, Wang Y, Hummon AB, Evans WE, Baker SD, Cavaletti G, Sparreboom A, Hu S. Li Y, et al. Among authors: chen m, chen x. JCI Insight. 2023 Jul 24;8(14):e164646. doi: 10.1172/jci.insight.164646. JCI Insight. 2023. PMID: 37347545 Free PMC article.
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