Chen M - Search Results

1

A proof of concept for structure-based vaccine design targeting RSV in humans.

Crank MC, Ruckwardt TJ, Chen M, Morabito KM, Phung E, Costner PJ, Holman LA, Hickman SP, Berkowitz NM, Gordon IJ, Yamshchikov GV, Gaudinski MR, Kumar A, Chang LA, Moin SM, Hill JP, DiPiazza AT, Schwartz RM, Kueltzo L, Cooper JW, Chen P, Stein JA, Carlton K, Gall JG, Nason MC, Kwong PD, Chen GL, Mascola JR, McLellan JS, Ledgerwood JE, Graham BS; VRC 317 Study Team. Crank MC, et al. Among authors: chen m, chen gl, chen p. Science. 2019 Aug 2;365(6452):505-509. doi: 10.1126/science.aav9033. Science. 2019. PMID: 31371616 Clinical Trial.

2

Modified vaccinia virus Ankara immunization protects against lethal challenge with recombinant vaccinia virus expressing murine interleukin-4.

McCurdy LH, Rutigliano JA, Johnson TR, Chen M, Graham BS. McCurdy LH, et al. Among authors: chen m. J Virol. 2004 Nov;78(22):12471-9. doi: 10.1128/JVI.78.22.12471-12479.2004. J Virol. 2004. PMID: 15507634 Free PMC article.

3

Characterization of respiratory syncytial virus M- and M2-specific CD4 T cells in a murine model.

Liu J, Ruckwardt TJ, Chen M, Johnson TR, Graham BS. Liu J, et al. Among authors: chen m. J Virol. 2009 May;83(10):4934-41. doi: 10.1128/JVI.02140-08. Epub 2009 Mar 4. J Virol. 2009. PMID: 19264776 Free PMC article.

4

TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity.

Johnson TR, Rao S, Seder RA, Chen M, Graham BS. Johnson TR, et al. Among authors: chen m. Vaccine. 2009 May 18;27(23):3045-52. doi: 10.1016/j.vaccine.2009.03.026. Epub 2009 Apr 3. Vaccine. 2009. PMID: 19428918 Free PMC article.

5

Structural basis of respiratory syncytial virus neutralization by motavizumab.

McLellan JS, Chen M, Kim A, Yang Y, Graham BS, Kwong PD. McLellan JS, et al. Among authors: chen m. Nat Struct Mol Biol. 2010 Feb;17(2):248-50. doi: 10.1038/nsmb.1723. Epub 2010 Jan 24. Nat Struct Mol Biol. 2010. PMID: 20098425 Free PMC article.

6

Epitope-specific regulatory CD4 T cells reduce virus-induced illness while preserving CD8 T-cell effector function at the site of infection.

Liu J, Ruckwardt TJ, Chen M, Nicewonger JD, Johnson TR, Graham BS. Liu J, et al. Among authors: chen m. J Virol. 2010 Oct;84(20):10501-9. doi: 10.1128/JVI.00963-10. Epub 2010 Aug 4. J Virol. 2010. PMID: 20686045 Free PMC article.

7

Responses against a subdominant CD8+ T cell epitope protect against immunopathology caused by a dominant epitope.

Ruckwardt TJ, Luongo C, Malloy AM, Liu J, Chen M, Collins PL, Graham BS. Ruckwardt TJ, et al. Among authors: chen m. J Immunol. 2010 Oct 15;185(8):4673-80. doi: 10.4049/jimmunol.1001606. Epub 2010 Sep 10. J Immunol. 2010. PMID: 20833834 Free PMC article.

8

Structure of a major antigenic site on the respiratory syncytial virus fusion glycoprotein in complex with neutralizing antibody 101F.

McLellan JS, Chen M, Chang JS, Yang Y, Kim A, Graham BS, Kwong PD. McLellan JS, et al. Among authors: chen m. J Virol. 2010 Dec;84(23):12236-44. doi: 10.1128/JVI.01579-10. Epub 2010 Sep 29. J Virol. 2010. PMID: 20881049 Free PMC article.

9

T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection.

Billam P, Bonaparte KL, Liu J, Ruckwardt TJ, Chen M, Ryder AB, Wang R, Dash P, Thomas PG, Graham BS. Billam P, et al. Among authors: chen m. J Biol Chem. 2011 Feb 11;286(6):4829-41. doi: 10.1074/jbc.M110.191437. Epub 2010 Nov 30. J Biol Chem. 2011. PMID: 21118816 Free PMC article.

10

Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus.

McLellan JS, Correia BE, Chen M, Yang Y, Graham BS, Schief WR, Kwong PD. McLellan JS, et al. Among authors: chen m. J Mol Biol. 2011 Jun 24;409(5):853-66. doi: 10.1016/j.jmb.2011.04.044. Epub 2011 Apr 27. J Mol Biol. 2011. PMID: 21549714 Free PMC article.

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