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Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity.
Mitroulis I, Ruppova K, Wang B, Chen LS, Grzybek M, Grinenko T, Eugster A, Troullinaki M, Palladini A, Kourtzelis I, Chatzigeorgiou A, Schlitzer A, Beyer M, Joosten LAB, Isermann B, Lesche M, Petzold A, Simons K, Henry I, Dahl A, Schultze JL, Wielockx B, Zamboni N, Mirtschink P, Coskun Ü, Hajishengallis G, Netea MG, Chavakis T. Mitroulis I, et al. Among authors: chen ls. Cell. 2018 Jan 11;172(1-2):147-161.e12. doi: 10.1016/j.cell.2017.11.034. Cell. 2018. PMID: 29328910 Free PMC article.
Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release.
Masjkur J, Arps-Forker C, Poser SW, Nikolakopoulou P, Toutouna L, Chenna R, Chavakis T, Chatzigeorgiou A, Chen LS, Dubrovska A, Choudhary P, Uphues I, Mark M, Bornstein SR, Androutsellis-Theotokis A. Masjkur J, et al. Among authors: chen ls. J Biol Chem. 2014 Dec 19;289(51):35503-16. doi: 10.1074/jbc.M114.590687. Epub 2014 Nov 4. J Biol Chem. 2014. PMID: 25371201 Free PMC article.
Developmental endothelial locus-1 modulates platelet-monocyte interactions and instant blood-mediated inflammatory reaction in islet transplantation.
Kourtzelis I, Kotlabova K, Lim JH, Mitroulis I, Ferreira A, Chen LS, Gercken B, Steffen A, Kemter E, Klotzsche-von Ameln A, Waskow C, Hosur K, Chatzigeorgiou A, Ludwig B, Wolf E, Hajishengallis G, Chavakis T. Kourtzelis I, et al. Among authors: chen ls. Thromb Haemost. 2016 Apr;115(4):781-8. doi: 10.1160/TH15-05-0429. Epub 2015 Dec 17. Thromb Haemost. 2016. PMID: 26676803 Free PMC article.
Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche.
Mitroulis I, Chen LS, Singh RP, Kourtzelis I, Economopoulou M, Kajikawa T, Troullinaki M, Ziogas A, Ruppova K, Hosur K, Maekawa T, Wang B, Subramanian P, Tonn T, Verginis P, von Bonin M, Wobus M, Bornhäuser M, Grinenko T, Di Scala M, Hidalgo A, Wielockx B, Hajishengallis G, Chavakis T. Mitroulis I, et al. Among authors: chen ls. J Clin Invest. 2017 Oct 2;127(10):3624-3639. doi: 10.1172/JCI92571. Epub 2017 Aug 28. J Clin Invest. 2017. PMID: 28846069 Free PMC article.
DEL-1 promotes macrophage efferocytosis and clearance of inflammation.
Kourtzelis I, Li X, Mitroulis I, Grosser D, Kajikawa T, Wang B, Grzybek M, von Renesse J, Czogalla A, Troullinaki M, Ferreira A, Doreth C, Ruppova K, Chen LS, Hosur K, Lim JH, Chung KJ, Grossklaus S, Tausche AK, Joosten LAB, Moutsopoulos NM, Wielockx B, Castrillo A, Korostoff JM, Coskun Ü, Hajishengallis G, Chavakis T. Kourtzelis I, et al. Among authors: chen ls. Nat Immunol. 2019 Jan;20(1):40-49. doi: 10.1038/s41590-018-0249-1. Epub 2018 Nov 19. Nat Immunol. 2019. PMID: 30455459 Free PMC article.
886 results