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Structure-based design of non-hypertrophic apelin receptor modulator.
Wang WW, Ji SY, Zhang W, Zhang J, Cai C, Hu R, Zang SK, Miao L, Xu H, Chen LN, Yang Z, Guo J, Qin J, Shen DD, Liang P, Zhang Y, Zhang Y. Wang WW, et al. Among authors: chen ln. Cell. 2024 Mar 14;187(6):1460-1475.e20. doi: 10.1016/j.cell.2024.02.004. Epub 2024 Feb 29. Cell. 2024. PMID: 38428423
Conformational transitions and activation of the adhesion receptor CD97.
Mao C, Zhao RJ, Dong YJ, Gao M, Chen LN, Zhang C, Xiao P, Guo J, Qin J, Shen DD, Ji SY, Zang SK, Zhang H, Wang WW, Shen Q, Sun JP, Zhang Y. Mao C, et al. Among authors: chen ln. Mol Cell. 2024 Feb 1;84(3):570-583.e7. doi: 10.1016/j.molcel.2023.12.020. Epub 2024 Jan 11. Mol Cell. 2024. PMID: 38215752
Cryo-EM structures of inactive and active GABAB receptor.
Mao C, Shen C, Li C, Shen DD, Xu C, Zhang S, Zhou R, Shen Q, Chen LN, Jiang Z, Liu J, Zhang Y. Mao C, et al. Among authors: chen ln. Cell Res. 2020 Jul;30(7):564-573. doi: 10.1038/s41422-020-0350-5. Epub 2020 Jun 3. Cell Res. 2020. PMID: 32494023 Free PMC article.
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor.
Sun W, Chen LN, Zhou Q, Zhao LH, Yang D, Zhang H, Cong Z, Shen DD, Zhao F, Zhou F, Cai X, Chen Y, Zhou Y, Gadgaard S, van der Velden WJC, Zhao S, Jiang Y, Rosenkilde MM, Xu HE, Zhang Y, Wang MW. Sun W, et al. Among authors: chen ln, chen y. Cell Res. 2020 Dec;30(12):1098-1108. doi: 10.1038/s41422-020-00442-0. Epub 2020 Nov 25. Cell Res. 2020. PMID: 33239759 Free PMC article.
Molecular basis for the activation of thyrotropin-releasing hormone receptor.
Ji SY, Dong YJ, Chen LN, Zang SK, Wang J, Shen DD, Guo J, Qin J, Zhang H, Wang WW, Shen Q, Zhang Y, Song Z, Mao C. Ji SY, et al. Among authors: chen ln. Cell Discov. 2022 Oct 25;8(1):116. doi: 10.1038/s41421-022-00477-0. Cell Discov. 2022. PMID: 36280665 Free PMC article. No abstract available.
Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Mao C, Gao M, Zang SK, Zhu Y, Shen DD, Chen LN, Yang L, Wang Z, Zhang H, Wang WW, Shen Q, Lu Y, Ma X, Zhang Y. Mao C, et al. Among authors: chen ln. Nat Commun. 2023 Nov 22;14(1):7620. doi: 10.1038/s41467-023-43537-z. Nat Commun. 2023. PMID: 37993467 Free PMC article.
243 results