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Autoantibodies from patients with kidney allograft vasculopathy stimulate a proinflammatory switch in endothelial cells and monocytes mediated via GPCR-directed PAR1-TNF-α signaling.
Moll G, Luecht C, Gyamfi MA, da Fonseca DLM, Wang P, Zhao H, Gong Z, Chen L, Ashraf MI, Heidecke H, Hackel AM, Dragun D, Budde K, Penack O, Riemekasten G, Cabral-Marques O, Witowski J, Catar R. Moll G, et al. Among authors: chen l. Front Immunol. 2023 Oct 30;14:1289744. doi: 10.3389/fimmu.2023.1289744. eCollection 2023. Front Immunol. 2023. PMID: 37965310 Free PMC article.
IL-6 Trans-Signaling Links Inflammation with Angiogenesis in the Peritoneal Membrane.
Catar R, Witowski J, Zhu N, Lücht C, Derrac Soria A, Uceda Fernandez J, Chen L, Jones SA, Fielding CA, Rudolf A, Topley N, Dragun D, Jörres A. Catar R, et al. Among authors: chen l. J Am Soc Nephrol. 2017 Apr;28(4):1188-1199. doi: 10.1681/ASN.2015101169. Epub 2016 Nov 11. J Am Soc Nephrol. 2017. PMID: 27837150 Free PMC article.
Tumour necrosis factor-alpha in uraemic serum promotes osteoblastic transition and calcification of vascular smooth muscle cells via extracellular signal-regulated kinases and activator protein 1/c-FOS-mediated induction of interleukin 6 expression.
Zickler D, Luecht C, Willy K, Chen L, Witowski J, Girndt M, Fiedler R, Storr M, Kamhieh-Milz J, Schoon J, Geissler S, Ringdén O, Schindler R, Moll G, Dragun D, Catar R. Zickler D, et al. Among authors: chen l. Nephrol Dial Transplant. 2018 Apr 1;33(4):574-585. doi: 10.1093/ndt/gfx316. Nephrol Dial Transplant. 2018. PMID: 29228352
Control of neutrophil influx during peritonitis by transcriptional cross-regulation of chemokine CXCL1 by IL-17 and IFN-γ.
Catar RA, Chen L, Cuff SM, Kift-Morgan A, Eberl M, Kettritz R, Kamhieh-Milz J, Moll G, Li Q, Zhao H, Kawka E, Zickler D, Parekh G, Davis P, Fraser DJ, Dragun D, Eckardt KU, Jörres A, Witowski J. Catar RA, et al. Among authors: chen l. J Pathol. 2020 Jun;251(2):175-186. doi: 10.1002/path.5438. Epub 2020 May 13. J Pathol. 2020. PMID: 32232854
Expanded Hemodialysis Therapy Ameliorates Uremia-Induced Systemic Microinflammation and Endothelial Dysfunction by Modulating VEGF, TNF-α and AP-1 Signaling.
Catar R, Moll G, Kamhieh-Milz J, Luecht C, Chen L, Zhao H, Ernst L, Willy K, Girndt M, Fiedler R, Witowski J, Morawietz H, Ringdén O, Dragun D, Eckardt KU, Schindler R, Zickler D. Catar R, et al. Among authors: chen l. Front Immunol. 2021 Nov 11;12:774052. doi: 10.3389/fimmu.2021.774052. eCollection 2021. Front Immunol. 2021. PMID: 34858433 Free PMC article.
Angiogenic Role of Mesothelium-Derived Chemokine CXCL1 During Unfavorable Peritoneal Tissue Remodeling in Patients Receiving Peritoneal Dialysis as Renal Replacement Therapy.
Catar RA, Bartosova M, Kawka E, Chen L, Marinovic I, Zhang C, Zhao H, Wu D, Zickler D, Stadnik H, Karczewski M, Kamhieh-Milz J, Jörres A, Moll G, Schmitt CP, Witowski J. Catar RA, et al. Among authors: chen l. Front Immunol. 2022 Feb 4;13:821681. doi: 10.3389/fimmu.2022.821681. eCollection 2022. Front Immunol. 2022. PMID: 35185912 Free PMC article.
Ang II Promotes ET-1 Production by Regulating NOX2 Activity Through Transcription Factor Oct-1.
Kamhieh-Milz J, Chen L, Goettsch C, Pfefferkorn AM, Hofmann A, Brunssen C, Müller GM, Walther T, Ashraf MI, Moll G, Morawietz H, Witowski J, Catar R. Kamhieh-Milz J, et al. Among authors: chen l. Arterioscler Thromb Vasc Biol. 2023 Aug;43(8):1429-1440. doi: 10.1161/ATVBAHA.122.318764. Epub 2023 Jun 29. Arterioscler Thromb Vasc Biol. 2023. PMID: 37381986
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