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A naturally isolated symbiotic bacterium suppresses flavivirus transmission by Aedes mosquitoes.
Zhang L, Wang D, Shi P, Li J, Niu J, Chen J, Wang G, Wu L, Chen L, Yang Z, Li S, Meng J, Ruan F, He Y, Zhao H, Ren Z, Wang Y, Liu Y, Shi X, Wang Y, Liu Q, Li J, Wang P, Wang J, Zhu Y, Cheng G. Zhang L, et al. Among authors: chen l. Science. 2024 Apr 19;384(6693):eadn9524. doi: 10.1126/science.adn9524. Epub 2024 Apr 19. Science. 2024. PMID: 38669573
Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity.
Zhang T, Yu W, Cheng X, Yeung J, Ahumada V, Norris PC, Pearson MJ, Yang X, van Deursen W, Halcovich C, Nassar A, Vesely MD, Zhang Y, Zhang J, Ji L, Flies DB, Liu L, Langermann S, LaRochelle WJ, Humphrey R, Zhao D, Zhang Q, Zhang J, Gu R, Schalper KA, Sanmamed MF, Chen L. Zhang T, et al. Among authors: chen l. Sci Immunol. 2024 Apr 26;9(94):eadh2334. doi: 10.1126/sciimmunol.adh2334. Epub 2024 Apr 26. Sci Immunol. 2024. PMID: 38669316
Design, Synthesis, and Investigation of the Pharmacokinetics and Anticancer Activities of Indenoisoquinoline Derivatives That Stabilize the G-Quadruplex in the MYC Promoter and Inhibit Topoisomerase I.
Han Y, Buric A, Chintareddy V, DeMoss M, Chen L, Dickerhoff J, De Dios R, Chand P, Riggs R, Yang D, Cushman M. Han Y, et al. Among authors: chen l. J Med Chem. 2024 Apr 26. doi: 10.1021/acs.jmedchem.3c02303. Online ahead of print. J Med Chem. 2024. PMID: 38668707
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