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Oxidative stress-triggered Wnt signaling perturbation characterizes the tipping point of lung adeno-to-squamous transdifferentiation.
Fang Z, Han X, Chen Y, Tong X, Xue Y, Yao S, Tang S, Pan Y, Sun Y, Wang X, Jin Y, Chen H, Hu L, Hui L, Li L, Chen L, Ji H. Fang Z, et al. Among authors: chen l, chen h, chen y. Signal Transduct Target Ther. 2023 Jan 11;8(1):16. doi: 10.1038/s41392-022-01227-0. Signal Transduct Target Ther. 2023. PMID: 36627278 Free PMC article.
Novel protein kinase inhibitor TT-00420 inhibits gallbladder cancer by inhibiting JNK/JUN-mediated signaling pathway.
Miao H, Geng Y, Li Y, Tang S, Feng F, Li W, Li Y, Liu L, Zhang R, Qiu S, Wu Y, Wang Z, Wang Z, Shao Z, Liu K, Zou L, Yang M, Zhao Y, Chen C, Li Z, Zhang D, Peng P, Qiang X, Wu F, He Y, Chen L, Xiang D, Jiang X, Li M, Liu Y, Liu Y. Miao H, et al. Among authors: chen l, chen c. Cell Oncol (Dordr). 2022 Aug;45(4):689-708. doi: 10.1007/s13402-022-00692-7. Epub 2022 Jul 23. Cell Oncol (Dordr). 2022. PMID: 35870050
Integrated characterization of hepatobiliary tumor organoids provides a potential landscape of pharmacogenomic interactions.
Zhu Y, Tang S, Yuan Q, Fu J, He J, Liu Z, Zhao X, Li Y, Zhao Y, Zhang Y, Zhang X, Zhang Y, Zhu Y, Wang W, Zheng B, Wu R, Wu T, Yang S, Qiu X, Shen S, Hu J, Chen L, Wang Y, Wang H, Gao D, Chen L. Zhu Y, et al. Among authors: chen l. Cell Rep Med. 2024 Feb 20;5(2):101375. doi: 10.1016/j.xcrm.2023.101375. Epub 2024 Jan 25. Cell Rep Med. 2024. PMID: 38278146 Free PMC article.
Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.
Tong X, Patel AS, Kim E, Li H, Chen Y, Li S, Liu S, Dilly J, Kapner KS, Zhang N, Xue Y, Hover L, Mukhopadhyay S, Sherman F, Myndzar K, Sahu P, Gao Y, Li F, Li F, Fang Z, Jin Y, Gao J, Shi M, Sinha S, Chen L, Chen Y, Kheoh T, Yang W, Yanai I, Moreira AL, Velcheti V, Neel BG, Hu L, Christensen JG, Olson P, Gao D, Zhang MQ, Aguirre AJ, Wong KK, Ji H. Tong X, et al. Among authors: chen l, chen y. Cancer Cell. 2024 Mar 11;42(3):413-428.e7. doi: 10.1016/j.ccell.2024.01.012. Epub 2024 Feb 22. Cancer Cell. 2024. PMID: 38402609 Free article.
Tracing steroidogenesis in prostate biopsy samples to unveil prostate tissue androgen metabolism characteristics and potential clinical application.
Hou Z, Yang T, Mei Z, Zhang S, Gao Y, Chen X, Tan Q, Zhu X, Xu C, Lian J, Bian C, Liu Y, Le W, Hydyr N, Wu D, Chen L, Huang S, Li Z. Hou Z, et al. Among authors: chen l, chen x. J Steroid Biochem Mol Biol. 2021 Jun;210:105859. doi: 10.1016/j.jsbmb.2021.105859. Epub 2021 Mar 4. J Steroid Biochem Mol Biol. 2021. PMID: 33677016
Multicellular ecotypes shape progression of lung adenocarcinoma from ground-glass opacity toward advanced stages.
Deng Y, Xia L, Zhang J, Deng S, Wang M, Wei S, Li K, Lai H, Yang Y, Bai Y, Liu Y, Luo L, Yang Z, Chen Y, Kang R, Gan F, Pu Q, Mei J, Ma L, Lin F, Guo C, Liao H, Zhu Y, Liu Z, Liu C, Hu Y, Yuan Y, Zha Z, Yuan G, Zhang G, Chen L, Cheng Q, Shen S, Liu L. Deng Y, et al. Among authors: chen l, chen y. Cell Rep Med. 2024 Apr 16;5(4):101489. doi: 10.1016/j.xcrm.2024.101489. Epub 2024 Mar 29. Cell Rep Med. 2024. PMID: 38554705 Free PMC article.
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