Chen L - Search Results

1

Crystal structure and cellular functions of uPAR dimer.

Yu S, Sui Y, Wang J, Li Y, Li H, Cao Y, Chen L, Jiang L, Yuan C, Huang M. Yu S, et al. Among authors: chen l. Nat Commun. 2022 Mar 29;13(1):1665. doi: 10.1038/s41467-022-29344-y. Nat Commun. 2022. PMID: 35351875 Free PMC article.

2

An anti-urokinase plasminogen activator receptor (uPAR) antibody: crystal structure and binding epitope.

Li Y, Parry G, Chen L, Callahan JA, Shaw DE, Meehan EJ, Mazar AP, Huang M. Li Y, et al. Among authors: chen l. J Mol Biol. 2007 Jan 26;365(4):1117-29. doi: 10.1016/j.jmb.2006.10.059. Epub 2006 Oct 21. J Mol Biol. 2007. PMID: 17101149

3

Insights into the serine protease mechanism based on structural observations of the conversion of a peptidyl serine protease inhibitor to a substrate.

Jiang L, Andersen LM, Andreasen PA, Chen L, Huang M. Jiang L, et al. Among authors: chen l. Biochim Biophys Acta. 2016 Mar;1860(3):599-606. doi: 10.1016/j.bbagen.2015.12.009. Epub 2015 Dec 12. Biochim Biophys Acta. 2016. PMID: 26691138

4

Optimization of crystals of an inhibitory antibody of urokinase plasminogen activator receptor (uPAR) with hydrogen peroxide and low protein concentration.

Li Y, Shi X, Parry G, Chen L, Callahan JA, Mazar AP, Huang M. Li Y, et al. Among authors: chen l. Protein Pept Lett. 2005 Oct;12(7):655-8. doi: 10.2174/0929866054696073. Protein Pept Lett. 2005. PMID: 16522179

5

An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg2+.

Rao Y, Bian C, Yuan C, Li Y, Chen L, Ye X, Huang Z, Huang M. Rao Y, et al. Among authors: chen l. Biochem Biophys Res Commun. 2006 Sep 29;348(3):908-15. doi: 10.1016/j.bbrc.2006.07.148. Epub 2006 Aug 1. Biochem Biophys Res Commun. 2006. PMID: 16899220

6

Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD.

Bian C, Yuan C, Chen L, Meehan EJ, Jiang L, Huang Z, Lin L, Huang M. Bian C, et al. Among authors: chen l. Proteins. 2010 May 1;78(6):1601-5. doi: 10.1002/prot.22676. Proteins. 2010. PMID: 20146362 No abstract available.

7

Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1.

Yuan C, Chen L, Meehan EJ, Daly N, Craik DJ, Huang M, Ngo JC. Yuan C, et al. Among authors: chen l. BMC Struct Biol. 2011 Jun 22;11:30. doi: 10.1186/1472-6807-11-30. BMC Struct Biol. 2011. PMID: 21693064 Free PMC article.

8

Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM).

Xu X, Cai Y, Wei Y, Donate F, Juarez J, Parry G, Chen L, Meehan EJ, Ahn RW, Ugolkov A, Dubrovskyi O, O'Halloran TV, Huang M, Mazar AP. Xu X, et al. Among authors: chen l. PLoS One. 2014 Jan 21;9(1):e85349. doi: 10.1371/journal.pone.0085349. eCollection 2014. PLoS One. 2014. PMID: 24465541 Free PMC article.

9

Structure of human urokinase plasminogen activator in complex with its receptor.

Huai Q, Mazar AP, Kuo A, Parry GC, Shaw DE, Callahan J, Li Y, Yuan C, Bian C, Chen L, Furie B, Furie BC, Cines DB, Huang M. Huai Q, et al. Among authors: chen l. Science. 2006 Feb 3;311(5761):656-9. doi: 10.1126/science.1121143. Science. 2006. PMID: 16456079

10

Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding.

Liu Z, Lin L, Yuan C, Nicolaes GA, Chen L, Meehan EJ, Furie B, Furie B, Huang M. Liu Z, et al. Among authors: chen l. J Biol Chem. 2010 Mar 19;285(12):8824-9. doi: 10.1074/jbc.M109.080168. Epub 2010 Jan 20. J Biol Chem. 2010. PMID: 20089867 Free PMC article.

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