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Systematic identification of genomic markers of drug sensitivity in cancer cells.
Garnett MJ, Edelman EJ, Heidorn SJ, Greenman CD, Dastur A, Lau KW, Greninger P, Thompson IR, Luo X, Soares J, Liu Q, Iorio F, Surdez D, Chen L, Milano RJ, Bignell GR, Tam AT, Davies H, Stevenson JA, Barthorpe S, Lutz SR, Kogera F, Lawrence K, McLaren-Douglas A, Mitropoulos X, Mironenko T, Thi H, Richardson L, Zhou W, Jewitt F, Zhang T, O'Brien P, Boisvert JL, Price S, Hur W, Yang W, Deng X, Butler A, Choi HG, Chang JW, Baselga J, Stamenkovic I, Engelman JA, Sharma SV, Delattre O, Saez-Rodriguez J, Gray NS, Settleman J, Futreal PA, Haber DA, Stratton MR, Ramaswamy S, McDermott U, Benes CH. Garnett MJ, et al. Among authors: chen l. Nature. 2012 Mar 28;483(7391):570-5. doi: 10.1038/nature11005. Nature. 2012. PMID: 22460902 Free PMC article.
PEA3 activates CXCR4 transcription in MDA-MB-231 and MCF7 breast cancer cells.
Gu S, Chen L, Hong Q, Yan T, Zhuang Z, Wang Q, Jin W, Zhu H, Wu J. Gu S, et al. Among authors: chen l. Acta Biochim Biophys Sin (Shanghai). 2011 Oct;43(10):771-8. doi: 10.1093/abbs/gmr070. Epub 2011 Aug 10. Acta Biochim Biophys Sin (Shanghai). 2011. PMID: 21831961 Free article.
Genome-wide analysis of YY2 versus YY1 target genes.
Chen L, Shioda T, Coser KR, Lynch MC, Yang C, Schmidt EV. Chen L, et al. Nucleic Acids Res. 2010 Jul;38(12):4011-26. doi: 10.1093/nar/gkq112. Epub 2010 Mar 9. Nucleic Acids Res. 2010. PMID: 20215434 Free PMC article.
The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers.
Yang C, Hayashida T, Forster N, Li C, Shen D, Maheswaran S, Chen L, Anderson KS, Ellisen LW, Sgroi D, Schmidt EV. Yang C, et al. Among authors: chen l. Cancer Res. 2011 Feb 1;71(3):937-45. doi: 10.1158/0008-5472.CAN-10-1471. Epub 2010 Dec 2. Cancer Res. 2011. PMID: 21127199 Free PMC article.
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