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The therapeutic potential of the Wnt signaling pathway in bone disorders.
Wagner ER, Zhu G, Zhang BQ, Luo Q, Shi Q, Huang E, Gao Y, Gao JL, Kim SH, Rastegar F, Yang K, He BC, Chen L, Zuo GW, Bi Y, Su Y, Luo J, Luo X, Huang J, Deng ZL, Reid RR, Luu HH, Haydon RC, He TC. Wagner ER, et al. Among authors: chen l. Curr Mol Pharmacol. 2011 Jan;4(1):14-25. Curr Mol Pharmacol. 2011. PMID: 20825362 Review.
BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling.
Tang N, Song WX, Luo J, Luo X, Chen J, Sharff KA, Bi Y, He BC, Huang JY, Zhu GH, Su YX, Jiang W, Tang M, He Y, Wang Y, Chen L, Zuo GW, Shen J, Pan X, Reid RR, Luu HH, Haydon RC, He TC. Tang N, et al. Among authors: chen j, chen l. J Cell Mol Med. 2009 Aug;13(8B):2448-2464. doi: 10.1111/j.1582-4934.2008.00569.x. Epub 2008 Nov 3. J Cell Mol Med. 2009. PMID: 19175684 Free PMC article.
BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential.
Luther G, Wagner ER, Zhu G, Kang Q, Luo Q, Lamplot J, Bi Y, Luo X, Luo J, Teven C, Shi Q, Kim SH, Gao JL, Huang E, Yang K, Rames R, Liu X, Li M, Hu N, Liu H, Su Y, Chen L, He BC, Zuo GW, Deng ZL, Reid RR, Luu HH, Haydon RC, He TC. Luther G, et al. Among authors: chen l. Curr Gene Ther. 2011 Jun;11(3):229-40. doi: 10.2174/156652311795684777. Curr Gene Ther. 2011. PMID: 21453282
Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells.
Sharff KA, Song WX, Luo X, Tang N, Luo J, Chen J, Bi Y, He BC, Huang J, Li X, Jiang W, Zhu GH, Su Y, He Y, Shen J, Wang Y, Chen L, Zuo GW, Liu B, Pan X, Reid RR, Luu HH, Haydon RC, He TC. Sharff KA, et al. Among authors: chen j, chen l. J Biol Chem. 2009 Jan 2;284(1):649-659. doi: 10.1074/jbc.M806389200. Epub 2008 Nov 5. J Biol Chem. 2009. PMID: 18986983 Free PMC article.
Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.
Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N. Bi Y, et al. Among authors: chen l. J Cell Biochem. 2009 Sep 1;108(1):295-303. doi: 10.1002/jcb.22254. J Cell Biochem. 2009. PMID: 19562671
Therapeutic Implications of PPARgamma in Human Osteosarcoma.
Wagner ER, He BC, Chen L, Zuo GW, Zhang W, Shi Q, Luo Q, Luo X, Liu B, Luo J, Rastegar F, He CJ, Hu Y, Boody B, Luu HH, He TC, Deng ZL, Haydon RC. Wagner ER, et al. Among authors: chen l. PPAR Res. 2010;2010:956427. doi: 10.1155/2010/956427. Epub 2010 Feb 16. PPAR Res. 2010. PMID: 20182546 Free PMC article.
Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation.
Chen L, Jiang W, Huang J, He BC, Zuo GW, Zhang W, Luo Q, Shi Q, Zhang BQ, Wagner ER, Luo J, Tang M, Wietholt C, Luo X, Bi Y, Su Y, Liu B, Kim SH, He CJ, Hu Y, Shen J, Rastegar F, Huang E, Gao Y, Gao JL, Zhou JZ, Reid RR, Luu HH, Haydon RC, He TC, Deng ZL. Chen L, et al. J Bone Miner Res. 2010 Nov;25(11):2447-59. doi: 10.1002/jbmr.133. J Bone Miner Res. 2010. PMID: 20499340 Free PMC article.
Retinoic acids potentiate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells.
Zhang W, Deng ZL, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Wagner ER, Rastegar F, Kim SH, Jiang W, Shen J, Huang E, Gao Y, Gao JL, Zhou JZ, Luo J, Huang J, Luo X, Bi Y, Su Y, Yang K, Liu H, Luu HH, Haydon RC, He TC, He BC. Zhang W, et al. Among authors: chen l. PLoS One. 2010 Jul 30;5(7):e11917. doi: 10.1371/journal.pone.0011917. PLoS One. 2010. PMID: 20689834 Free PMC article.
Lysophosphatidic acid acyltransferase β (LPAATβ) promotes the tumor growth of human osteosarcoma.
Rastegar F, Gao JL, Shenaq D, Luo Q, Shi Q, Kim SH, Jiang W, Wagner ER, Huang E, Gao Y, Shen J, Yang K, He BC, Chen L, Zuo GW, Luo J, Luo X, Bi Y, Liu X, Li M, Hu N, Wang L, Luther G, Luu HH, Haydon RC, He TC. Rastegar F, et al. Among authors: chen l. PLoS One. 2010 Dec 1;5(12):e14182. doi: 10.1371/journal.pone.0014182. PLoS One. 2010. PMID: 21152068 Free PMC article.
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