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Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis.
Su TH, Shiau CW, Jao P, Yang NJ, Tai WT, Liu CJ, Tseng TC, Yang HC, Liu CH, Huang KW, Hu TC, Huang YJ, Wu YM, Chen LJ, Chen PJ, Chen DS, Chen KF, Kao JH. Su TH, et al. Among authors: chen lj, chen ds, chen pj, chen kf. Sci Rep. 2017 May 11;7(1):1728. doi: 10.1038/s41598-017-01572-z. Sci Rep. 2017. PMID: 28496142 Free PMC article.
Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition.
Su TH, Shiau CW, Jao P, Liu CH, Liu CJ, Tai WT, Jeng YM, Yang HC, Tseng TC, Huang HP, Cheng HR, Chen PJ, Chen KF, Kao JH, Chen DS. Su TH, et al. Among authors: chen ds, chen pj, chen kf. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7243-8. doi: 10.1073/pnas.1507499112. Epub 2015 May 26. Proc Natl Acad Sci U S A. 2015. PMID: 26039995 Free PMC article.
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