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Neoantigen Cancer Vaccines and Different Immune Checkpoint Therapies Each Utilize Both Converging and Distinct Mechanisms that in Combination Enable Synergistic Therapeutic Efficacy.
Keshari S, Shavkunov AS, Miao Q, Saha A, Williams CD, Highsmith AM, Pineda JE, Alspach E, Hu KH, Pauken KE, Chen K, Gubin MM. Keshari S, et al. Among authors: chen k. bioRxiv [Preprint]. 2024 Jan 26:2023.12.20.570816. doi: 10.1101/2023.12.20.570816. bioRxiv. 2024. PMID: 38187708 Free PMC article. Preprint.
Generation of glucocorticoid resistant SARS-CoV-2 T-cells for adoptive cell therapy.
Basar R, Uprety N, Ensley E, Daher M, Klein K, Martinez F, Aung F, Shanley M, Hu B, Gokdemir E, Mendt M, Silva FR, Acharya S, Laskowski T, Muniz-Feliciano L, Banerjee P, Li Y, Li S, Garcia LM, Lin P, Shaim H, Yates SG, Marin D, Kaur I, Rao S, Mak D, Lin A, Miao Q, Dou J, Chen K, Champlin R, Shpall EJ, Rezvani K. Basar R, et al. Among authors: chen k. bioRxiv [Preprint]. 2020 Sep 15:2020.09.15.298547. doi: 10.1101/2020.09.15.298547. bioRxiv. 2020. PMID: 32995792 Free PMC article. Updated. Preprint.
BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy.
Salmon AJ, Shavkunov AS, Miao Q, Jarjour NN, Keshari S, Esaulova E, Williams CD, Ward JP, Highsmith AM, Pineda JE, Taneja R, Chen K, Edelson BT, Gubin MM. Salmon AJ, et al. Among authors: chen k. Cancer Immunol Res. 2022 May 3;10(5):597-611. doi: 10.1158/2326-6066.CIR-21-0129. Cancer Immunol Res. 2022. PMID: 35181783 Free PMC article.
Ab initio spillover compensation in mass cytometry data.
Miao Q, Wang F, Dou J, Iqbal R, Muftuoglu M, Basar R, Li L, Rezvani K, Chen K. Miao Q, et al. Among authors: chen k. Cytometry A. 2021 Sep;99(9):899-909. doi: 10.1002/cyto.a.24298. Epub 2020 Dec 31. Cytometry A. 2021. PMID: 33342071 Free PMC article.
Bi-order multimodal integration of single-cell data.
Dou J, Liang S, Mohanty V, Miao Q, Huang Y, Liang Q, Cheng X, Kim S, Choi J, Li Y, Li L, Daher M, Basar R, Rezvani K, Chen R, Chen K. Dou J, et al. Among authors: chen k, chen r. Genome Biol. 2022 May 9;23(1):112. doi: 10.1186/s13059-022-02679-x. Genome Biol. 2022. PMID: 35534898 Free PMC article.
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+ B cell tumors: a phase 1/2 trial.
Marin D, Li Y, Basar R, Rafei H, Daher M, Dou J, Mohanty V, Dede M, Nieto Y, Uprety N, Acharya S, Liu E, Wilson J, Banerjee P, Macapinlac HA, Ganesh C, Thall PF, Bassett R, Ammari M, Rao S, Cao K, Shanley M, Kaplan M, Hosing C, Kebriaei P, Nastoupil LJ, Flowers CR, Moseley SM, Lin P, Ang S, Popat UR, Qazilbash MH, Champlin RE, Chen K, Shpall EJ, Rezvani K. Marin D, et al. Among authors: chen k. Nat Med. 2024 Mar;30(3):772-784. doi: 10.1038/s41591-023-02785-8. Epub 2024 Jan 18. Nat Med. 2024. PMID: 38238616 Free PMC article. Clinical Trial.
A novel immature natural killer cell subpopulation predicts relapse after cord blood transplantation.
Li L, Chen H, Marin D, Xi Y, Miao Q, Lv J, Banerjee PP, Shaim H, Daher M, Basar R, Imahashi N, Jimenez J, Hu B, Mehta RS, Kerbauy LN, Kaplan M, Mendt M, Ozcan G, Gokdemir E, Hernandez Sanabria M, Li Y, Chen K, Wang J, Muniz-Feliciano L, Zhao WL, Champlin RE, Shpall EJ, Rezvani K. Li L, et al. Among authors: chen k, chen h. Blood Adv. 2019 Dec 10;3(23):4117-4130. doi: 10.1182/bloodadvances.2019000835. Blood Adv. 2019. PMID: 31821460 Free PMC article.
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