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Pathogenic autoantibodies to IFN-γ act through the impedance of receptor assembly and Fc-mediated response.
Shih HP, Ding JY, Sotolongo Bellón J, Lo YF, Chung PH, Ting HT, Peng JJ, Wu TY, Lin CH, Lo CC, Lin YN, Yeh CF, Chen JB, Wu TS, Liu YM, Kuo CY, Wang SY, Tu KH, Ng CY, Lei WT, Tsai YH, Chen JH, Chuang YT, Huang JY, Rey FA, Chen HK, Chang TW, Piehler J, Chi CY, Ku CL. Shih HP, et al. Among authors: chen jh, chen hk, chen jb. J Exp Med. 2022 Sep 5;219(9):e20212126. doi: 10.1084/jem.20212126. Epub 2022 Jul 14. J Exp Med. 2022. PMID: 35833912 Free PMC article.
Antibodies and superantibodies in patients with chronic rhinosinusitis with nasal polyps.
Chen JB, James LK, Davies AM, Wu YB, Rimmer J, Lund VJ, Chen JH, McDonnell JM, Chan YC, Hutchins GH, Chang TW, Sutton BJ, Kariyawasam HH, Gould HJ. Chen JB, et al. Among authors: chen jh. J Allergy Clin Immunol. 2017 Apr;139(4):1195-1204.e11. doi: 10.1016/j.jaci.2016.06.066. Epub 2016 Sep 19. J Allergy Clin Immunol. 2017. PMID: 27658758 Free PMC article.
IgE-neutralizing UB-221 mAb, distinct from omalizumab and ligelizumab, exhibits CD23-mediated IgE downregulation and relieves urticaria symptoms.
Kuo BS, Li CH, Chen JB, Shiung YY, Chu CY, Lee CH, Liu YJ, Kuo JH, Hsu C, Su HW, Li YF, Lai A, Ho YF, Cheng YN, Huang HX, Lung MC, Wu MS, Yang FH, Lin CH, Tseng W, Yang J, Lin CY, Tsai PH, Chang HK, Wang YJ, Chen T, Lynn S, Liao MJ, Wang CY. Kuo BS, et al. Among authors: chen jb, chen t. J Clin Invest. 2022 Aug 1;132(15):e157765. doi: 10.1172/JCI157765. J Clin Invest. 2022. PMID: 35912861 Free PMC article.
636 results