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In vitro generation of mouse morula-like cells.
Li H, Chang L, Wu J, Huang J, Guan W, Bates LE, Stuart HT, Guo M, Zhang P, Huang B, Chen C, Zhang M, Chen J, Min M, Wu G, Hutchins AP, Silva JCR. Li H, et al. Among authors: chen j, chen c. Dev Cell. 2023 Nov 20;58(22):2510-2527.e7. doi: 10.1016/j.devcel.2023.09.013. Epub 2023 Oct 23. Dev Cell. 2023. PMID: 37875119
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells.
Esteban MA, Wang T, Qin B, Yang J, Qin D, Cai J, Li W, Weng Z, Chen J, Ni S, Chen K, Li Y, Liu X, Xu J, Zhang S, Li F, He W, Labuda K, Song Y, Peterbauer A, Wolbank S, Redl H, Zhong M, Cai D, Zeng L, Pei D. Esteban MA, et al. Among authors: chen j, chen k. Cell Stem Cell. 2010 Jan 8;6(1):71-9. doi: 10.1016/j.stem.2009.12.001. Epub 2009 Dec 31. Cell Stem Cell. 2010. PMID: 20036631 Free article.
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters.
Bao X, Wu H, Zhu X, Guo X, Hutchins AP, Luo Z, Song H, Chen Y, Lai K, Yin M, Xu L, Zhou L, Chen J, Wang D, Qin B, Frampton J, Tse HF, Pei D, Wang H, Zhang B, Esteban MA. Bao X, et al. Among authors: chen j, chen y. Cell Res. 2015 Jan;25(1):80-92. doi: 10.1038/cr.2014.165. Epub 2014 Dec 16. Cell Res. 2015. PMID: 25512341 Free PMC article.
The oncogene c-Jun impedes somatic cell reprogramming.
Liu J, Han Q, Peng T, Peng M, Wei B, Li D, Wang X, Yu S, Yang J, Cao S, Huang K, Hutchins AP, Liu H, Kuang J, Zhou Z, Chen J, Wu H, Guo L, Chen Y, Chen Y, Li X, Wu H, Liao B, He W, Song H, Yao H, Pan G, Chen J, Pei D. Liu J, et al. Among authors: chen j, chen y. Nat Cell Biol. 2015 Jul;17(7):856-67. doi: 10.1038/ncb3193. Epub 2015 Jun 22. Nat Cell Biol. 2015. PMID: 26098572
Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function.
Zhou Z, Yang X, He J, Liu J, Wu F, Yu S, Liu Y, Lin R, Liu H, Cui Y, Zhou C, Wang X, Wu J, Cao S, Guo L, Lin L, Wang T, Peng X, Qiang B, Hutchins AP, Pei D, Chen J. Zhou Z, et al. Among authors: chen j. Cell Rep. 2017 Nov 21;21(8):2160-2170. doi: 10.1016/j.celrep.2017.10.091. Cell Rep. 2017. PMID: 29166607 Free article.
Chromatin Accessibility Dynamics during iPSC Reprogramming.
Li D, Liu J, Yang X, Zhou C, Guo J, Wu C, Qin Y, Guo L, He J, Yu S, Liu H, Wang X, Wu F, Kuang J, Hutchins AP, Chen J, Pei D. Li D, et al. Among authors: chen j. Cell Stem Cell. 2017 Dec 7;21(6):819-833.e6. doi: 10.1016/j.stem.2017.10.012. Cell Stem Cell. 2017. PMID: 29220666 Free article.
Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-Seq.
Guo L, Lin L, Wang X, Gao M, Cao S, Mai Y, Wu F, Kuang J, Liu H, Yang J, Chu S, Song H, Li D, Liu Y, Wu K, Liu J, Wang J, Pan G, Hutchins AP, Liu J, Pei D, Chen J. Guo L, et al. Among authors: chen j. Mol Cell. 2019 Feb 21;73(4):815-829.e7. doi: 10.1016/j.molcel.2019.01.042. Epub 2019 Feb 13. Mol Cell. 2019. PMID: 30772174 Free article.
Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2.
Malik V, Glaser LV, Zimmer D, Velychko S, Weng M, Holzner M, Arend M, Chen Y, Srivastava Y, Veerapandian V, Shah Z, Esteban MA, Wang H, Chen J, Schöler HR, Hutchins AP, Meijsing SH, Pott S, Jauch R. Malik V, et al. Among authors: chen j, chen y. Nat Commun. 2019 Aug 2;10(1):3477. doi: 10.1038/s41467-019-11054-7. Nat Commun. 2019. PMID: 31375664 Free PMC article.
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