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Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters.
Zhang L, Jiang Y, He J, Chen J, Qi R, Yuan L, Shao T, Zhao H, Chen C, Chen Y, Wang X, Lei X, Gao Q, Zhuang C, Zhou M, Ma J, Liu W, Yang M, Fu R, Wu Y, Chen F, Xiong H, Nie M, Chen Y, Wu K, Fang M, Wang Y, Zheng Z, Huang S, Ge S, Cheng SC, Zhu H, Cheng T, Yuan Q, Wu T, Zhang J, Chen Y, Zhang T, Li C, Qi H, Guan Y, Xia N. Zhang L, et al. Among authors: chen j, chen c, chen f, chen y. Nat Commun. 2023 Jul 11;14(1):4117. doi: 10.1038/s41467-023-39560-9. Nat Commun. 2023. PMID: 37433761 Free PMC article.
A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses.
Shen C, Chen J, Li R, Zhang M, Wang G, Stegalkina S, Zhang L, Chen J, Cao J, Bi X, Anderson SF, Alefantis T, Zhang M, Cai X, Yang K, Zheng Q, Fang M, Yu H, Luo W, Zheng Z, Yuan Q, Zhang J, Wai-Kuo Shih J, Kleanthous H, Chen H, Chen Y, Xia N. Shen C, et al. Among authors: chen j, chen h, chen y. Sci Transl Med. 2017 Oct 18;9(412):eaam5752. doi: 10.1126/scitranslmed.aam5752. Sci Transl Med. 2017. PMID: 29046433
An IgM antibody targeting the receptor binding site of influenza B blocks viral infection with great breadth and potency.
Shen C, Zhang M, Chen Y, Zhang L, Wang G, Chen J, Chen S, Li Z, Wei F, Chen J, Yang K, Guo S, Wang Y, Zheng Q, Yu H, Luo W, Zhang J, Chen H, Chen Y, Xia N. Shen C, et al. Among authors: chen j, chen s, chen h, chen y. Theranostics. 2019 Jan 1;9(1):210-231. doi: 10.7150/thno.28434. eCollection 2019. Theranostics. 2019. PMID: 30662563 Free PMC article.
A prophylactic effect of aluminium-based adjuvants against respiratory viruses via priming local innate immunity.
Wang X, Yin X, Zhang B, Liu C, Lin Y, Huang X, Li Y, Shen C, Zheng W, Fu G, Chen J, Wen Y, Zhang W, Pan BS, Fang M, Zheng Z, Zhang Z, Yuan Q, Fu G, Li S, Zhang J, Chen Y, Xia N, Zhao Q. Wang X, et al. Among authors: chen j, chen y. Emerg Microbes Infect. 2022 Dec;11(1):914-925. doi: 10.1080/22221751.2022.2050951. Emerg Microbes Infect. 2022. PMID: 35254215 Free PMC article.
A Neutralizing Antibody Targeting gH Provides Potent Protection against EBV Challenge In Vivo.
Hong J, Zhong L, Zheng Q, Wu Q, Zha Z, Wei D, Chen H, Zhang W, Zhang S, Huang Y, Chen K, Chen J, Li S, Zeng MS, Zeng YX, Xia N, Zhang X, Xu M, Chen Y. Hong J, et al. Among authors: chen j, chen k, chen h, chen y. J Virol. 2022 Apr 27;96(8):e0007522. doi: 10.1128/jvi.00075-22. Epub 2022 Mar 29. J Virol. 2022. PMID: 35348362 Free PMC article.
A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2.
Chen J, Wang P, Yuan L, Zhang L, Zhang L, Zhao H, Chen C, Wang X, Han J, Chen Y, Jia J, Lu Z, Hong J, Lu Z, Wang Q, Chen R, Qi R, Ma J, Zhou M, Yu H, Zhuang C, Liu X, Han Q, Wang G, Su Y, Yuan Q, Cheng T, Wu T, Ye X, Zhang T, Li C, Zhang J, Zhu H, Chen Y, Chen H, Xia N. Chen J, et al. Among authors: chen r, chen c, chen h, chen y. Sci Bull (Beijing). 2022 Jul 15;67(13):1372-1387. doi: 10.1016/j.scib.2022.05.018. Epub 2022 May 26. Sci Bull (Beijing). 2022. PMID: 35637645 Free PMC article.
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