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Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas.
Scheich S, Chen J, Liu J, Schnütgen F, Enssle JC, Ceribelli M, Thomas CJ, Choi J, Morris V, Hsiao T, Nguyen H, Wang B, Bolomsky A, Phelan JD, Corcoran S, Urlaub H, Young RM, Häupl B, Wright GW, Huang DW, Ji Y, Yu X, Xu W, Yang Y, Zhao H, Muppidi J, Pan KT, Oellerich T, Staudt LM. Scheich S, et al. Among authors: chen j. Cancer Discov. 2023 Aug 4;13(8):1862-1883. doi: 10.1158/2159-8290.CD-22-1401. Cancer Discov. 2023. PMID: 37141112 Free PMC article.
Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex.
Sun Y, Baechler SA, Zhang X, Kumar S, Factor VM, Arakawa Y, Chau CH, Okamoto K, Parikh A, Walker B, Su YP, Chen J, Ting T, Huang SN, Beck E, Itkin Z, McKnight C, Xie C, Roper N, Nijhawan D, Figg WD, Meltzer PS, Yang JC, Thomas CJ, Pommier Y. Sun Y, et al. Among authors: chen j. Nat Commun. 2023 Jun 23;14(1):3762. doi: 10.1038/s41467-023-39374-9. Nat Commun. 2023. PMID: 37353483 Free PMC article.
Incorporating the image formation process into deep learning improves network performance.
Li Y, Su Y, Guo M, Han X, Liu J, Vishwasrao HD, Li X, Christensen R, Sengupta T, Moyle MW, Rey-Suarez I, Chen J, Upadhyaya A, Usdin TB, Colón-Ramos DA, Liu H, Wu Y, Shroff H. Li Y, et al. Among authors: chen j. Nat Methods. 2022 Nov;19(11):1427-1437. doi: 10.1038/s41592-022-01652-7. Epub 2022 Oct 31. Nat Methods. 2022. PMID: 36316563 Free PMC article.
Multiview confocal super-resolution microscopy.
Wu Y, Han X, Su Y, Glidewell M, Daniels JS, Liu J, Sengupta T, Rey-Suarez I, Fischer R, Patel A, Combs C, Sun J, Wu X, Christensen R, Smith C, Bao L, Sun Y, Duncan LH, Chen J, Pommier Y, Shi YB, Murphy E, Roy S, Upadhyaya A, Colón-Ramos D, La Riviere P, Shroff H. Wu Y, et al. Among authors: chen j. Nature. 2021 Dec;600(7888):279-284. doi: 10.1038/s41586-021-04110-0. Epub 2021 Nov 26. Nature. 2021. PMID: 34837071 Free PMC article.
Plasticity in structure and assembly of SARS-CoV-2 nucleocapsid protein.
Zhao H, Nguyen A, Wu D, Li Y, Hassan SA, Chen J, Shroff H, Piszczek G, Schuck P. Zhao H, et al. Among authors: chen j. PNAS Nexus. 2022 May 16;1(2):pgac049. doi: 10.1093/pnasnexus/pgac049. eCollection 2022 May. PNAS Nexus. 2022. PMID: 35783502 Free PMC article.
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