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RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer.
Deng P, Wang Z, Chen J, Liu S, Yao X, Liu S, Liu L, Yu Z, Huang Y, Xiong Z, Xiao R, Gao J, Liang W, Chen J, Liu H, Hong JH, Chan JY, Guan P, Chen J, Wang Y, Yin J, Li J, Zheng M, Zhang C, Zhou P, Kang T, Teh BT, Yu Q, Zuo Z, Jiang Q, Liu J, Xiong Y, Xia X, Tan J. Deng P, et al. Among authors: chen j. J Clin Invest. 2022 Nov 15;132(22):e159628. doi: 10.1172/JCI159628. J Clin Invest. 2022. PMID: 36201246 Free PMC article.
Targeting enhancer reprogramming to mitigate MEK inhibitor resistance in preclinical models of advanced ovarian cancer.
Liu S, Zou Q, Chen JP, Yao X, Guan P, Liang W, Deng P, Lai X, Yin J, Chen J, Chen R, Yu Z, Xiao R, Sun Y, Hong JH, Liu H, Lu H, Chen J, Bei JX, Koh J, Chan JY, Wang B, Kang T, Yu Q, Teh BT, Liu J, Xiong Y, Tan J. Liu S, et al. Among authors: chen j, chen r, chen jp. J Clin Invest. 2021 Oct 15;131(20):e145035. doi: 10.1172/JCI145035. J Clin Invest. 2021. PMID: 34464356 Free PMC article.
Tumor PD-L1 expression is correlated with increased TILs and poor prognosis in penile squamous cell carcinoma.
Deng C, Li Z, Guo S, Chen P, Chen X, Zhou Q, Chen J, Yu X, Wu X, Ma W, Xie Q, Ye Y, Li Y, Qin Z, Liu Z, Liu R, Zhang Z, Yao K, Han H, Zhou F. Deng C, et al. Among authors: chen j, chen p, chen x. Oncoimmunology. 2016 Dec 22;6(2):e1269047. doi: 10.1080/2162402X.2016.1269047. eCollection 2017. Oncoimmunology. 2016. PMID: 28344882 Free PMC article.
Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia.
Huang L, Liu D, Wang N, Ling S, Tang Y, Wu J, Hao L, Luo H, Hu X, Sheng L, Zhu L, Wang D, Luo Y, Shang Z, Xiao M, Mao X, Zhou K, Cao L, Dong L, Zheng X, Sui P, He J, Mo S, Yan J, Ao Q, Qiu L, Zhou H, Liu Q, Zhang H, Li J, Jin J, Fu L, Zhao W, Chen J, Du X, Qing G, Liu H, Liu X, Huang G, Ma D, Zhou J, Wang QF. Huang L, et al. Among authors: chen j. Cell Res. 2018 Feb;28(2):172-186. doi: 10.1038/cr.2017.146. Epub 2017 Nov 17. Cell Res. 2018. PMID: 29148541 Free PMC article.
Up-regulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression and catalytic activity is associated with immunosuppression and poor prognosis in penile squamous cell carcinoma patients.
Zhou QH, Han H, Lu JB, Liu TY, Huang KB, Deng CZ, Li ZS, Chen JP, Yao K, Qin ZK, Liu ZW, Li YH, Guo SJ, Ye YL, Zhou FJ, Liu RY. Zhou QH, et al. Cancer Commun (Lond). 2020 Jan;40(1):3-15. doi: 10.1002/cac2.12001. Epub 2020 Mar 3. Cancer Commun (Lond). 2020. PMID: 32125093 Free PMC article.
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