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High-dimensional analysis of the murine myeloid cell system.
Becher B, Schlitzer A, Chen J, Mair F, Sumatoh HR, Teng KW, Low D, Ruedl C, Riccardi-Castagnoli P, Poidinger M, Greter M, Ginhoux F, Newell EW. Becher B, et al. Among authors: chen j. Nat Immunol. 2014 Dec;15(12):1181-9. doi: 10.1038/ni.3006. Epub 2014 Oct 12. Nat Immunol. 2014. PMID: 25306126
C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages.
Hoeffel G, Chen J, Lavin Y, Low D, Almeida FF, See P, Beaudin AE, Lum J, Low I, Forsberg EC, Poidinger M, Zolezzi F, Larbi A, Ng LG, Chan JK, Greter M, Becher B, Samokhvalov IM, Merad M, Ginhoux F. Hoeffel G, et al. Among authors: chen j. Immunity. 2015 Apr 21;42(4):665-78. doi: 10.1016/j.immuni.2015.03.011. Immunity. 2015. PMID: 25902481 Free PMC article.
Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow.
Schlitzer A, Sivakamasundari V, Chen J, Sumatoh HR, Schreuder J, Lum J, Malleret B, Zhang S, Larbi A, Zolezzi F, Renia L, Poidinger M, Naik S, Newell EW, Robson P, Ginhoux F. Schlitzer A, et al. Among authors: chen j. Nat Immunol. 2015 Jul;16(7):718-28. doi: 10.1038/ni.3200. Epub 2015 Jun 8. Nat Immunol. 2015. PMID: 26054720
Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species.
Guilliams M, Dutertre CA, Scott CL, McGovern N, Sichien D, Chakarov S, Van Gassen S, Chen J, Poidinger M, De Prijck S, Tavernier SJ, Low I, Irac SE, Mattar CN, Sumatoh HR, Low GHL, Chung TJK, Chan DKH, Tan KK, Hon TLK, Fossum E, Bogen B, Choolani M, Chan JKY, Larbi A, Luche H, Henri S, Saeys Y, Newell EW, Lambrecht BN, Malissen B, Ginhoux F. Guilliams M, et al. Among authors: chen j. Immunity. 2016 Sep 20;45(3):669-684. doi: 10.1016/j.immuni.2016.08.015. Epub 2016 Sep 13. Immunity. 2016. PMID: 27637149 Free PMC article.
CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.
Chong SZ, Evrard M, Devi S, Chen J, Lim JY, See P, Zhang Y, Adrover JM, Lee B, Tan L, Li JL, Liong KH, Phua C, Balachander A, Boey A, Liebl D, Tan SM, Chan JK, Balabanian K, Harris JE, Bianchini M, Weber C, Duchene J, Lum J, Poidinger M, Chen Q, Rénia L, Wang CI, Larbi A, Randolph GJ, Weninger W, Looney MR, Krummel MF, Biswas SK, Ginhoux F, Hidalgo A, Bachelerie F, Ng LG. Chong SZ, et al. Among authors: chen j, chen q. J Exp Med. 2016 Oct 17;213(11):2293-2314. doi: 10.1084/jem.20160800. Epub 2016 Oct 10. J Exp Med. 2016. PMID: 27811056 Free PMC article.
Mapping the human DC lineage through the integration of high-dimensional techniques.
See P, Dutertre CA, Chen J, Günther P, McGovern N, Irac SE, Gunawan M, Beyer M, Händler K, Duan K, Sumatoh HRB, Ruffin N, Jouve M, Gea-Mallorquí E, Hennekam RCM, Lim T, Yip CC, Wen M, Malleret B, Low I, Shadan NB, Fen CFS, Tay A, Lum J, Zolezzi F, Larbi A, Poidinger M, Chan JKY, Chen Q, Rénia L, Haniffa M, Benaroch P, Schlitzer A, Schultze JL, Newell EW, Ginhoux F. See P, et al. Among authors: chen j, chen q. Science. 2017 Jun 9;356(6342):eaag3009. doi: 10.1126/science.aag3009. Epub 2017 May 4. Science. 2017. PMID: 28473638 Free PMC article.
Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease.
Tan-Garcia A, Wai LE, Zheng D, Ceccarello E, Jo J, Banu N, Khakpoor A, Chia A, Tham CYL, Tan AT, Hong M, Keng CT, Rivino L, Tan KC, Lee KH, Lim SG, Newell EW, Pavelka N, Chen J, Ginhoux F, Chen Q, Bertoletti A, Dutertre CA. Tan-Garcia A, et al. Among authors: chen j, chen q. J Hepatol. 2017 Sep;67(3):490-500. doi: 10.1016/j.jhep.2017.04.023. Epub 2017 May 5. J Hepatol. 2017. PMID: 28483682
Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.
Takata K, Kozaki T, Lee CZW, Thion MS, Otsuka M, Lim S, Utami KH, Fidan K, Park DS, Malleret B, Chakarov S, See P, Low D, Low G, Garcia-Miralles M, Zeng R, Zhang J, Goh CC, Gul A, Hubert S, Lee B, Chen J, Low I, Shadan NB, Lum J, Wei TS, Mok E, Kawanishi S, Kitamura Y, Larbi A, Poidinger M, Renia L, Ng LG, Wolf Y, Jung S, Önder T, Newell E, Huber T, Ashihara E, Garel S, Pouladi MA, Ginhoux F. Takata K, et al. Among authors: chen j. Immunity. 2017 Jul 18;47(1):183-198.e6. doi: 10.1016/j.immuni.2017.06.017. Immunity. 2017. PMID: 28723550 Free article.
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