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Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels.
Murray A, Gough G, Cindrić A, Vučković F, Koschut D, Borelli V, Petrović DJ, Bekavac A, Plećaš A, Hribljan V, Brunmeir R, Jurić J, Pučić-Baković M, Slana A, Deriš H, Frkatović A, Groet J, O'Brien NL, Chen HY, Yeap YJ, Delom F, Havlicek S, Gammon L, Hamburg S, Startin C, D'Souza H, Mitrečić D, Kero M, Odak L, Krušlin B, Krsnik Ž, Kostović I, Foo JN, Loh YH, Dunn NR, de la Luna S, Spector T, Barišić I, Thomas MSC, Strydom A, Franceschi C, Lauc G, Krištić J, Alić I, Nižetić D. Murray A, et al. Among authors: chen hy. EBioMedicine. 2023 Aug;94:104692. doi: 10.1016/j.ebiom.2023.104692. Epub 2023 Jul 12. EBioMedicine. 2023. PMID: 37451904 Free PMC article.
Improved erythroid differentiation of multiple human pluripotent stem cell lines in microcarrier culture by modulation of Wnt/β-Catenin signaling.
Sivalingam J, Chen HY, Yang BX, Lim ZR, Lam ATL, Woo TL, Chen AK, Reuveny S, Loh YH, Oh SK. Sivalingam J, et al. Among authors: chen hy, chen ak. Haematologica. 2018 Jul;103(7):e279-e283. doi: 10.3324/haematol.2017.180919. Epub 2018 Mar 8. Haematologica. 2018. PMID: 29519863 Free PMC article. No abstract available.
A Scalable Suspension Platform for Generating High-Density Cultures of Universal Red Blood Cells from Human Induced Pluripotent Stem Cells.
Sivalingam J, SuE Y, Lim ZR, Lam ATL, Lee AP, Lim HL, Chen HY, Tan HK, Warrier T, Hang JW, Nazir NB, Tan AHM, Renia L, Loh YH, Reuveny S, Malleret B, Oh SKW. Sivalingam J, et al. Among authors: chen hy. Stem Cell Reports. 2021 Jan 12;16(1):182-197. doi: 10.1016/j.stemcr.2020.11.008. Epub 2020 Dec 10. Stem Cell Reports. 2021. PMID: 33306988 Free PMC article.
Data Format Standardization and DICOM Integration for Hyperpolarized 13C MRI.
Diaz E, Sriram R, Gordon JW, Sinha A, Liu X, Sahin SI, Crane JC, Olson MP, Chen HY, Bernard JML, Vigneron DB, Wang ZJ, Xu D, Larson PEZ. Diaz E, et al. Among authors: chen hy. J Imaging Inform Med. 2024 May 6. doi: 10.1007/s10278-024-01100-2. Online ahead of print. J Imaging Inform Med. 2024. PMID: 38710970
4,874 results