Chen HW - Search Results

1

Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells.

Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. Candas-Green D, et al. Among authors: chen hw. Nat Commun. 2020 Sep 14;11(1):4591. doi: 10.1038/s41467-020-18245-7. Nat Commun. 2020. PMID: 32929084 Free PMC article.

2

Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance.

Zou JX, Duan Z, Wang J, Sokolov A, Xu J, Chen CZ, Li JJ, Chen HW. Zou JX, et al. Among authors: chen hw, chen cz. Mol Cancer Res. 2014 Apr;12(4):539-49. doi: 10.1158/1541-7786.MCR-13-0459. Epub 2014 Jan 3. Mol Cancer Res. 2014. PMID: 24391143 Free PMC article.

3

Wang Y, Stokes A, Duan Z, Hui J, Xu Y, Chen Y, Chen HW, Lam K, Zhou CJ. Wang Y, et al. Among authors: chen hw, chen y. J Am Soc Nephrol. 2016 Feb;27(2):417-27. doi: 10.1681/ASN.2014100998. Epub 2015 Jun 5. J Am Soc Nephrol. 2016. PMID: 26047795 Free PMC article.

4

ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer.

Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, Evans RM, Xu Y, Chen HW. Wang J, et al. Among authors: chen hw. Nat Med. 2016 May;22(5):488-96. doi: 10.1038/nm.4070. Epub 2016 Mar 28. Nat Med. 2016. PMID: 27019329 Free PMC article.

5

Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes.

Wang J, Duan Z, Nugent Z, Zou JX, Borowsky AD, Zhang Y, Tepper CG, Li JJ, Fiehn O, Xu J, Kung HJ, Murphy LC, Chen HW. Wang J, et al. Among authors: chen hw. Cancer Lett. 2016 Aug 10;378(2):69-79. doi: 10.1016/j.canlet.2016.05.004. Epub 2016 May 6. Cancer Lett. 2016. PMID: 27164560 Free PMC article.

6

Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer.

Liu C, Lou W, Yang JC, Liu L, Armstrong CM, Lombard AP, Zhao R, Noel ODV, Tepper CG, Chen HW, Dall'Era M, Evans CP, Gao AC. Liu C, et al. Among authors: chen hw. Nat Commun. 2018 Nov 16;9(1):4700. doi: 10.1038/s41467-018-07178-x. Nat Commun. 2018. PMID: 30446660 Free PMC article.

7

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype.

Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. Cai D, et al. Among authors: chen hw, chen x. Nat Commun. 2019 Oct 11;10(1):4621. doi: 10.1038/s41467-019-12529-3. Nat Commun. 2019. PMID: 31604910 Free PMC article.

8

Targeting bromodomain protein ANCCA/ATAD2 enhances the efficacy of DNA‑damaging chemotherapy agents and radiation.

Duan Z, Andrews NP, Chen CZ, Fan M, Wang J, Shen J, Li JJ, Chen HW. Duan Z, et al. Among authors: chen hw, chen cz. Oncol Rep. 2020 Jan;43(1):318-327. doi: 10.3892/or.2019.7418. Epub 2019 Nov 27. Oncol Rep. 2020. PMID: 31789405

9

CPT1A/2-Mediated FAO Enhancement-A Metabolic Target in Radioresistant Breast Cancer.

Han S, Wei R, Zhang X, Jiang N, Fan M, Huang JH, Xie B, Zhang L, Miao W, Butler AC, Coleman MA, Vaughan AT, Wang Y, Chen HW, Liu J, Li JJ. Han S, et al. Among authors: chen hw. Front Oncol. 2019 Nov 15;9:1201. doi: 10.3389/fonc.2019.01201. eCollection 2019. Front Oncol. 2019. PMID: 31803610 Free PMC article.

10

Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade.

Liu L, Xie B, Fan M, Candas-Green D, Jiang JX, Wei R, Wang Y, Chen HW, Hu Y, Li JJ. Liu L, et al. Among authors: chen hw. Dev Cell. 2020 Jan 27;52(2):196-209.e9. doi: 10.1016/j.devcel.2019.11.012. Epub 2019 Dec 19. Dev Cell. 2020. PMID: 31866205 Free PMC article.

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