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Mechanistic insights into mitochondrial tRNAAla 3'-end metabolism deficiency.
Ji Y, Nie Z, Meng F, Hu C, Chen H, Jin L, Chen M, Zhang M, Zhang J, Liang M, Wang M, Guan MX. Ji Y, et al. Among authors: chen m, chen h. J Biol Chem. 2021 Jul;297(1):100816. doi: 10.1016/j.jbc.2021.100816. Epub 2021 May 21. J Biol Chem. 2021. PMID: 34023389 Free PMC article.
Chromatin remodeling: demethylating H3K4me3 of type I IFNs gene by Rbp2 through interacting with Piasy for transcriptional attenuation.
Yu X, Chen H, Zuo C, Jin X, Yin Y, Wang H, Jin M, Ozato K, Xu S. Yu X, et al. Among authors: chen h. FASEB J. 2018 Feb;32(2):552-567. doi: 10.1096/fj.201700088RR. Epub 2018 Jan 4. FASEB J. 2018. PMID: 28970247 Free PMC article.
Our study demonstrates that Piasy may prevent exaggerated transcription of IFNI by Rbp2-mediated demethylation of H3K4me3 of IFNI, avoiding excessive immune responses.-Yu, X., Chen, H., Zuo, C., Jin, X., Yin, Y., Wang, H., Jin, M., Ozato, K., Xu, S. ...
Our study demonstrates that Piasy may prevent exaggerated transcription of IFNI by Rbp2-mediated demethylation of H3K4me3 of IFNI, avoiding …
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