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Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.
AbuHammad S, Cullinane C, Martin C, Bacolas Z, Ward T, Chen H, Slater A, Ardley K, Kirby L, Chan KT, Brajanovski N, Smith LK, Rao AD, Lelliott EJ, Kleinschmidt M, Vergara IA, Papenfuss AT, Lau P, Ghosh P, Haupt S, Haupt Y, Sanij E, Poortinga G, Pearson RB, Falk H, Curtis DJ, Stupple P, Devlin M, Street I, Davies MA, McArthur GA, Sheppard KE. AbuHammad S, et al. Among authors: chen h. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17990-18000. doi: 10.1073/pnas.1901323116. Epub 2019 Aug 22. Proc Natl Acad Sci U S A. 2019. PMID: 31439820 Free PMC article.
Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker.
Fischer GM, Carapeto FCL, Joon AY, Haydu LE, Chen H, Wang F, Van Arnam JS, McQuade JL, Wani K, Kirkwood JM, Thompson JF, Tetzlaff MT, Lazar AJ, Tawbi HA, Gershenwald JE, Scolyer RA, Long GV, Davies MA. Fischer GM, et al. Among authors: chen h. Cancer Med. 2020 Nov;9(22):8650-8661. doi: 10.1002/cam4.3474. Epub 2020 Oct 5. Cancer Med. 2020. PMID: 33016647 Free PMC article.
Biomarkers of response to Akt inhibitor MK-2206 in breast cancer.
Sangai T, Akcakanat A, Chen H, Tarco E, Wu Y, Do KA, Miller TW, Arteaga CL, Mills GB, Gonzalez-Angulo AM, Meric-Bernstam F. Sangai T, et al. Among authors: chen h. Clin Cancer Res. 2012 Oct 15;18(20):5816-28. doi: 10.1158/1078-0432.CCR-12-1141. Epub 2012 Aug 29. Clin Cancer Res. 2012. PMID: 22932669 Free PMC article.
3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib.
Meraz IM, Majidi M, Fang B, Meng F, Gao L, Shao R, Song R, Li F, Lissanu Y, Chen H, Ha MJ, Wang Q, Wang J, Shpall E, Jung SY, Haderk F, Gui P, Riess JW, Olivas V, Bivona TG, Roth JA. Meraz IM, et al. Among authors: chen h. Commun Biol. 2023 May 11;6(1):509. doi: 10.1038/s42003-023-04889-w. Commun Biol. 2023. PMID: 37169941 Free PMC article.
Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancer.
Luyimbazi D, Akcakanat A, McAuliffe PF, Zhang L, Singh G, Gonzalez-Angulo AM, Chen H, Do KA, Zheng Y, Hung MC, Mills GB, Meric-Bernstam F. Luyimbazi D, et al. Among authors: chen h. Mol Cancer Ther. 2010 Oct;9(10):2770-84. doi: 10.1158/1535-7163.MCT-09-0980. Epub 2010 Sep 28. Mol Cancer Ther. 2010. PMID: 20876744 Free PMC article.
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