Chen G - Search Results

1

Genetic variants in CYP2A6 and UGT1A9 genes associated with urinary nicotine metabolites in young Mexican smokers.

Borrego-Soto G, Perez-Paramo YX, Chen G, Santuario-Facio SK, Santos-Guzman J, Posadas-Valay R, Alvarado-Monroy FM, Balderas-Renteria I, Medina-Gonzalez R, Ortiz-Lopez R, Lazarus P, Rojas-Martinez A. Borrego-Soto G, et al. Among authors: chen g. Pharmacogenomics J. 2020 Aug;20(4):586-594. doi: 10.1038/s41397-020-0147-4. Epub 2020 Jan 21. Pharmacogenomics J. 2020. PMID: 31959879 Free PMC article.

2

Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform.

Dellinger RW, Fang JL, Chen G, Weinberg R, Lazarus P. Dellinger RW, et al. Among authors: chen g. Drug Metab Dispos. 2006 Jun;34(6):943-9. doi: 10.1124/dmd.105.009100. Epub 2006 Mar 1. Drug Metab Dispos. 2006. PMID: 16510539

3

Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants.

Sun D, Chen G, Dellinger RW, Duncan K, Fang JL, Lazarus P. Sun D, et al. Among authors: chen g. Breast Cancer Res. 2006;8(4):R50. doi: 10.1186/bcr1539. Breast Cancer Res. 2006. PMID: 16884532 Free PMC article.

4

Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation.

Zheng Y, Sun D, Sharma AK, Chen G, Amin S, Lazarus P. Zheng Y, et al. Among authors: chen g. Drug Metab Dispos. 2007 Oct;35(10):1942-8. doi: 10.1124/dmd.107.016279. Epub 2007 Jul 9. Drug Metab Dispos. 2007. PMID: 17620345

5

Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism.

Chen G, Blevins-Primeau AS, Dellinger RW, Muscat JE, Lazarus P. Chen G, et al. Cancer Res. 2007 Oct 1;67(19):9024-9. doi: 10.1158/0008-5472.CAN-07-2245. Cancer Res. 2007. PMID: 17909004

6

Glucuronidation of tobacco-specific nitrosamines by UGT2B10.

Chen G, Dellinger RW, Sun D, Spratt TE, Lazarus P. Chen G, et al. Drug Metab Dispos. 2008 May;36(5):824-30. doi: 10.1124/dmd.107.019406. Epub 2008 Jan 31. Drug Metab Dispos. 2008. PMID: 18238858 Free PMC article.

7

Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines.

Chen G, Dellinger RW, Gallagher CJ, Sun D, Lazarus P. Chen G, et al. Pharmacogenet Genomics. 2008 Mar;18(3):181-91. doi: 10.1097/FPC.0b013e3282f4dbdd. Pharmacogenet Genomics. 2008. PMID: 18300939

8

Effects of menthol on tobacco smoke exposure, nicotine dependence, and NNAL glucuronidation.

Muscat JE, Chen G, Knipe A, Stellman SD, Lazarus P, Richie JP Jr. Muscat JE, et al. Among authors: chen g. Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):35-41. doi: 10.1158/1055-9965.EPI-08-0744. Cancer Epidemiol Biomarkers Prev. 2009. PMID: 19124478 Free PMC article.

9

Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites.

Blevins-Primeau AS, Sun D, Chen G, Sharma AK, Gallagher CJ, Amin S, Lazarus P. Blevins-Primeau AS, et al. Among authors: chen g. Cancer Res. 2009 Mar 1;69(5):1892-900. doi: 10.1158/0008-5472.CAN-08-3708. Epub 2009 Feb 24. Cancer Res. 2009. PMID: 19244109 Free PMC article.

10

Characterization of UGTs active against SAHA and association between SAHA glucuronidation activity phenotype with UGT genotype.

Balliet RM, Chen G, Gallagher CJ, Dellinger RW, Sun D, Lazarus P. Balliet RM, et al. Among authors: chen g. Cancer Res. 2009 Apr 1;69(7):2981-9. doi: 10.1158/0008-5472.CAN-08-4143. Epub 2009 Mar 24. Cancer Res. 2009. PMID: 19318555 Free PMC article.

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