Chen FX - Search Results

1

Coordinated regulation of RNA polymerase II pausing and elongation progression by PAF1.

Wang Z, Song A, Xu H, Hu S, Tao B, Peng L, Wang J, Li J, Yu J, Wang L, Li Z, Chen X, Wang M, Chi Y, Wu J, Xu Y, Zheng H, Chen FX. Wang Z, et al. Among authors: chen fx, chen x. Sci Adv. 2022 Apr;8(13):eabm5504. doi: 10.1126/sciadv.abm5504. Epub 2022 Apr 1. Sci Adv. 2022. PMID: 35363521 Free PMC article.

2

Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.

Zheng H, Qi Y, Hu S, Cao X, Xu C, Yin Z, Chen X, Li Y, Liu W, Li J, Wang J, Wei G, Liang K, Chen FX, Xu Y. Zheng H, et al. Among authors: chen fx, chen x. Science. 2020 Nov 27;370(6520):eabb5872. doi: 10.1126/science.abb5872. Science. 2020. PMID: 33243860

3

SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape.

Hu S, Peng L, Xu C, Wang Z, Song A, Chen FX. Hu S, et al. Among authors: chen fx. Mol Cell. 2021 Nov 4;81(21):4425-4439.e6. doi: 10.1016/j.molcel.2021.08.029. Epub 2021 Sep 16. Mol Cell. 2021. PMID: 34534457 Free article.

4

RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.

Wang X, Qi Y, Wang Z, Wang L, Song A, Tao B, Li J, Zhao D, Zhang H, Jin Q, Jiang YZ, Chen FX, Xu Y, Chen X. Wang X, et al. Among authors: chen fx, chen x. Cell Rep. 2022 Apr 26;39(4):110732. doi: 10.1016/j.celrep.2022.110732. Cell Rep. 2022. PMID: 35476980 Free article.

5

The pleiotropic roles of SPT5 in transcription.

Song A, Chen FX. Song A, et al. Among authors: chen fx. Transcription. 2022 Feb-Jun;13(1-3):53-69. doi: 10.1080/21541264.2022.2103366. Epub 2022 Jul 25. Transcription. 2022. PMID: 35876486 Free PMC article. Review.

6

H3K4me2/3 modulate the stability of RNA polymerase II pausing.

Hu S, Song A, Peng L, Tang N, Qiao Z, Wang Z, Lan F, Chen FX. Hu S, et al. Among authors: chen fx. Cell Res. 2023 May;33(5):403-406. doi: 10.1038/s41422-023-00794-3. Epub 2023 Mar 15. Cell Res. 2023. PMID: 36922644 Free PMC article. No abstract available.

7

R-loop-dependent promoter-proximal termination ensures genome stability.

Xu C, Li C, Chen J, Xiong Y, Qiao Z, Fan P, Li C, Ma S, Liu J, Song A, Tao B, Xu T, Xu W, Chi Y, Xue J, Wang P, Ye D, Gu H, Zhang P, Wang Q, Xiao R, Cheng J, Zheng H, Yu X, Zhang Z, Wu J, Liang K, Liu YJ, Lu H, Chen FX. Xu C, et al. Among authors: chen j, chen fx. Nature. 2023 Sep;621(7979):610-619. doi: 10.1038/s41586-023-06515-5. Epub 2023 Aug 9. Nature. 2023. PMID: 37557913 Free PMC article.

8

PAF1 regulation of promoter-proximal pause release via enhancer activation.

Chen FX, Xie P, Collings CK, Cao K, Aoi Y, Marshall SA, Rendleman EJ, Ugarenko M, Ozark PA, Zhang A, Shiekhattar R, Smith ER, Zhang MQ, Shilatifard A. Chen FX, et al. Science. 2017 Sep 22;357(6357):1294-1298. doi: 10.1126/science.aan3269. Epub 2017 Aug 31. Science. 2017. PMID: 28860207 Free PMC article.

9

Born to run: control of transcription elongation by RNA polymerase II.

Chen FX, Smith ER, Shilatifard A. Chen FX, et al. Nat Rev Mol Cell Biol. 2018 Jul;19(7):464-478. doi: 10.1038/s41580-018-0010-5. Nat Rev Mol Cell Biol. 2018. PMID: 29740129 Review.

10

PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II.

Chen FX, Woodfin AR, Gardini A, Rickels RA, Marshall SA, Smith ER, Shiekhattar R, Shilatifard A. Chen FX, et al. Cell. 2015 Aug 27;162(5):1003-15. doi: 10.1016/j.cell.2015.07.042. Epub 2015 Aug 13. Cell. 2015. PMID: 26279188 Free PMC article.

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