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High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.
Datta S, Chen DY, Tavares AH, Reyes-Robles T, Ryu KA, Khan N, Bechtel TJ, Bertoch JM, White CH, Hazuda DJ, Vora KA, Hett EC, Fadeyi OO, Oslund RC, Emili A, Saeed M. Datta S, et al. Among authors: chen dy. Cell Chem Biol. 2023 Oct 19;30(10):1313-1322.e7. doi: 10.1016/j.chembiol.2023.06.028. Epub 2023 Jul 26. Cell Chem Biol. 2023. PMID: 37499664
A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction.
Ejemel M, Li Q, Hou S, Schiller ZA, Tree JA, Wallace A, Amcheslavsky A, Kurt Yilmaz N, Buttigieg KR, Elmore MJ, Godwin K, Coombes N, Toomey JR, Schneider R, Ramchetty AS, Close BJ, Chen DY, Conway HL, Saeed M, Ganesa C, Carroll MW, Cavacini LA, Klempner MS, Schiffer CA, Wang Y. Ejemel M, et al. Among authors: chen dy. Nat Commun. 2020 Aug 21;11(1):4198. doi: 10.1038/s41467-020-18058-8. Nat Commun. 2020. PMID: 32826914 Free PMC article.
SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway.
Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Kapell S, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Connor JH, Douam F, Emili A, Saeed M. Chen DY, et al. Among authors: chen cs. bioRxiv [Preprint]. 2020 Oct 28:2020.10.27.358259. doi: 10.1101/2020.10.27.358259. bioRxiv. 2020. PMID: 33140044 Free PMC article. Preprint.
The in-vitro effect of famotidine on sars-cov-2 proteases and virus replication.
Loffredo M, Lucero H, Chen DY, O'Connell A, Bergqvist S, Munawar A, Bandara A, De Graef S, Weeks SD, Douam F, Saeed M, Munawar AH. Loffredo M, et al. Among authors: chen dy. Sci Rep. 2021 Mar 8;11(1):5433. doi: 10.1038/s41598-021-84782-w. Sci Rep. 2021. PMID: 33686143 Free PMC article.
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs.
Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Gallagher KME, Bauer MR, Taylor HB, Dunn WA, Tarr C, Sidney J, Rachimi S, Conway HL, Katsis K, Wang Y, Leistritz-Edwards D, Durkin MR, Tomkins-Tinch CH, Finkel Y, Nachshon A, Gentili M, Rivera KD, Carulli IP, Chea VA, Chandrashekar A, Bozkus CC, Carrington M; MGH COVID-19 Collection & Processing Team; Bhardwaj N, Barouch DH, Sette A, Maus MV, Rice CM, Clauser KR, Keskin DB, Pregibon DC, Hacohen N, Carr SA, Abelin JG, Saeed M, Sabeti PC. Weingarten-Gabbay S, et al. Among authors: chen dy. Cell. 2021 Jul 22;184(15):3962-3980.e17. doi: 10.1016/j.cell.2021.05.046. Epub 2021 Jun 3. Cell. 2021. PMID: 34171305 Free PMC article.
SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway.
Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Fuchs SY, Connor JH, Douam F, Emili A, Saeed M. Chen DY, et al. Among authors: chen cs. J Virol. 2021 Sep 9;95(19):e0086221. doi: 10.1128/JVI.00862-21. Epub 2021 Sep 9. J Virol. 2021. PMID: 34260266 Free PMC article.
Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.
Ren W, Zhu Y, Lan J, Chen H, Wang Y, Shi H, Feng F, Chen DY, Close B, Zhao X, Wu J, Tian B, Yuan Z, Zhou D, Saeed M, Wang X, Zhang R, Ding Q. Ren W, et al. Among authors: chen dy, chen h. J Virol. 2022 Jan 12;96(1):e0149221. doi: 10.1128/JVI.01492-21. Epub 2021 Oct 20. J Virol. 2022. PMID: 34668773 Free PMC article.
Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo.
Torchia JA, Tavares AH, Carstensen LS, Chen DY, Huang J, Xiao T, Mukherjee S, Reeves PM, Tu H, Sluder AE, Chen B, Kotton DN, Bowen RA, Saeed M, Poznansky MC, Freeman GJ. Torchia JA, et al. Among authors: chen dy, chen b. Sci Adv. 2022 Dec 9;8(49):eabq6527. doi: 10.1126/sciadv.abq6527. Epub 2022 Dec 7. Sci Adv. 2022. PMID: 36475798 Free PMC article.
1,429 results