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The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway.
Xu Y, Chen D, Lin XX, Zhao Q, Guo J, Chen LJ, Zhang W, Xiao J, Lian GH, Peng SF, Guo D, Yang H, Obianom O, Shu Y, Chen Y. Xu Y, et al. Among authors: chen lj, chen d, chen y. Arch Toxicol. 2019 Jun;93(6):1679-1695. doi: 10.1007/s00204-019-02447-0. Epub 2019 Apr 11. Arch Toxicol. 2019. PMID: 30976847
Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-Cyp2e1 Signaling.
Chen LJ, Lin XX, Guo J, Xu Y, Zhang SX, Chen D, Zhao Q, Xiao J, Lian GH, Peng SF, Guo D, Yang H, Shu Y, Zhou HH, Zhang W, Chen Y. Chen LJ, et al. Among authors: chen d, chen y. Int J Biol Sci. 2021 Sep 21;17(14):3936-3953. doi: 10.7150/ijbs.63732. eCollection 2021. Int J Biol Sci. 2021. PMID: 34671210 Free PMC article.
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