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Restoration of Foxp3+ Regulatory T Cells by HDAC-Dependent Epigenetic Modulation Plays a Pivotal Role in Resolving Pulmonary Arterial Hypertension Pathology.
Chen CN, Hajji N, Yeh FC, Rahman S, Ali S, Wharton J, Baxan N, Zhao L, Xie CY, Chen YG, Frid MG, Chelladurai P, Pullamsetti SS, Stenmark KR, Wilkins MR, Zhao L. Chen CN, et al. Among authors: chen yg. Am J Respir Crit Care Med. 2023 Oct 15;208(8):879-895. doi: 10.1164/rccm.202301-0181OC. Am J Respir Crit Care Med. 2023. PMID: 37676930
Isoform-specific characterization of class I histone deacetylases and their therapeutic modulation in pulmonary hypertension.
Chelladurai P, Dabral S, Basineni SR, Chen CN, Schmoranzer M, Bender N, Feld C, Nötzold RR, Dobreva G, Wilhelm J, Jungblut B, Zhao L, Bauer UM, Seeger W, Pullamsetti SS. Chelladurai P, et al. Among authors: chen cn. Sci Rep. 2020 Jul 30;10(1):12864. doi: 10.1038/s41598-020-69737-x. Sci Rep. 2020. PMID: 32733053 Free PMC article.
The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.
Zhao L, Oliver E, Maratou K, Atanur SS, Dubois OD, Cotroneo E, Chen CN, Wang L, Arce C, Chabosseau PL, Ponsa-Cobas J, Frid MG, Moyon B, Webster Z, Aldashev A, Ferrer J, Rutter GA, Stenmark KR, Aitman TJ, Wilkins MR. Zhao L, et al. Among authors: chen cn. Nature. 2015 Aug 20;524(7565):356-60. doi: 10.1038/nature14620. Epub 2015 Aug 10. Nature. 2015. PMID: 26258299 Free PMC article.
SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension.
Walters R, Vasilaki E, Aman J, Chen CN, Wu Y, Liang OD, Ashek A, Dubois O, Zhao L, Sabrin F, Cebola I, Ferrer J, Morrell NW, Klinger JR, Wilkins MR, Zhao L, Rhodes CJ. Walters R, et al. Among authors: chen cn. Circulation. 2023 May 23;147(21):1606-1621. doi: 10.1161/CIRCULATIONAHA.122.061940. Epub 2023 Apr 17. Circulation. 2023. PMID: 37066790 Free PMC article.
Response to letter regarding article, “histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid”.
Zhao L, Chen CN, Hajji N, Oliver E, Cotroneo E, Wharton J, Wilkins MR, Wang D, Li M, Stenmark KR, McKinsey TA, Buttrick P. Zhao L, et al. Among authors: chen cn. Circulation. 2013 Apr 9;127(14):e540. doi: 10.1161/circulationaha.112.154757. Circulation. 2013. PMID: 23691553 No abstract available.
556 results