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TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice.
Uthaya Kumar DB, Chen CL, Liu JC, Feldman DE, Sher LS, French S, DiNorcia J, French SW, Naini BV, Junrungsee S, Agopian VG, Zarrinpar A, Machida K. Uthaya Kumar DB, et al. Among authors: chen cl. Gastroenterology. 2016 Mar;150(3):707-19. doi: 10.1053/j.gastro.2015.11.002. Epub 2015 Nov 12. Gastroenterology. 2016. PMID: 26582088 Free PMC article.
p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs.
Choi HY, Siddique HR, Zheng M, Kou Y, Yeh DW, Machida T, Chen CL, Uthaya Kumar DB, Punj V, Winer P, Pita A, Sher L, Tahara SM, Ray RB, Liang C, Chen L, Tsukamoto H, Machida K. Choi HY, et al. Among authors: chen l, chen cl. Nat Commun. 2020 Jun 17;11(1):3084. doi: 10.1038/s41467-020-16616-8. Nat Commun. 2020. PMID: 32555153 Free PMC article.
c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity.
Serna R, Ramrakhiani A, Hernandez JC, Chen CL, Nakagawa C, Machida T, Ray RB, Zhan X, Tahara SM, Machida K. Serna R, et al. Among authors: chen cl. iScience. 2022 Apr 29;25(6):104325. doi: 10.1016/j.isci.2022.104325. eCollection 2022 Jun 17. iScience. 2022. PMID: 35601917 Free PMC article.
4,435 results