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Bioengineered bile ducts recapitulate key cholangiocyte functions.
Chen C, Jochems PGM, Salz L, Schneeberger K, Penning LC, van de Graaf SFJ, Beuers U, Clevers H, Geijsen N, Masereeuw R, Spee B. Chen C, et al. Biofabrication. 2018 Jun 12;10(3):034103. doi: 10.1088/1758-5090/aac8fd. Biofabrication. 2018. PMID: 29848792
Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids.
Nantasanti S, Spee B, Kruitwagen HS, Chen C, Geijsen N, Oosterhoff LA, van Wolferen ME, Pelaez N, Fieten H, Wubbolts RW, Grinwis GC, Chan J, Huch M, Vries RRG, Clevers H, de Bruin A, Rothuizen J, Penning LC, Schotanus BA. Nantasanti S, et al. Among authors: chen c. Stem Cell Reports. 2015 Nov 10;5(5):895-907. doi: 10.1016/j.stemcr.2015.09.002. Epub 2015 Oct 8. Stem Cell Reports. 2015. PMID: 26455412 Free PMC article.
Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells.
Schneeberger K, Sánchez-Romero N, Ye S, van Steenbeek FG, Oosterhoff LA, Pla Palacin I, Chen C, van Wolferen ME, van Tienderen G, Lieshout R, Colemonts-Vroninks H, Schene I, Hoekstra R, Verstegen MMA, van der Laan LJW, Penning LC, Fuchs SA, Clevers H, De Kock J, Baptista PM, Spee B. Schneeberger K, et al. Among authors: chen c. Hepatology. 2020 Jul;72(1):257-270. doi: 10.1002/hep.31037. Epub 2020 Apr 8. Hepatology. 2020. PMID: 31715015 Free PMC article.
Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease.
Kruitwagen HS, Oosterhoff LA, van Wolferen ME, Chen C, Nantasanti Assawarachan S, Schneeberger K, Kummeling A, van Straten G, Akkerdaas IC, Vinke CR, van Steenbeek FG, van Bruggen LWL, Wolfswinkel J, Grinwis GCM, Fuchs SA, Gehart H, Geijsen N, Vries RG, Clevers H, Rothuizen J, Schotanus BA, Penning LC, Spee B. Kruitwagen HS, et al. Among authors: chen c. Cells. 2020 Feb 11;9(2):410. doi: 10.3390/cells9020410. Cells. 2020. PMID: 32053895 Free PMC article.
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