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Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial.
Vlaar APJ, Witzenrath M, van Paassen P, Heunks LMA, Mourvillier B, de Bruin S, Lim EHT, Brouwer MC, Tuinman PR, Saraiva JFK, Marx G, Lobo SM, Boldo R, Simon-Campos JA, Cornet AD, Grebenyuk A, Engelbrecht JM, Mukansi M, Jorens PG, Zerbib R, Rückinger S, Pilz K, Guo R, van de Beek D, Riedemann NC; PANAMO study group. Vlaar APJ, et al. Lancet Respir Med. 2022 Dec;10(12):1137-1146. doi: 10.1016/S2213-2600(22)00297-1. Epub 2022 Sep 7. Lancet Respir Med. 2022. PMID: 36087611 Free PMC article. Clinical Trial.
Community-acquired Haemophilus influenzae meningitis in adults.
Chekrouni N, Koelman DLH, Brouwer MC, van der Ende A, van de Beek D. Chekrouni N, et al. J Infect. 2021 May;82(5):145-150. doi: 10.1016/j.jinf.2021.03.016. Epub 2021 Mar 25. J Infect. 2021. PMID: 33774020 Free article.
Community-acquired Staphylococcus aureus meningitis in adults.
van Soest TM, Søndermølle MB, Brouwer MC, Chekrouni N, Larsen AR, Petersen A, van Sorge NM, Nielsen H, van de Beek D, Bodilsen J; DASGIB study group. van Soest TM, et al. Among authors: chekrouni n. J Infect. 2023 Mar;86(3):239-244. doi: 10.1016/j.jinf.2023.01.022. Epub 2023 Jan 20. J Infect. 2023. PMID: 36682629
Cross-reactive antibodies after SARS-CoV-2 infection and vaccination.
Grobben M, van der Straten K, Brouwer PJ, Brinkkemper M, Maisonnasse P, Dereuddre-Bosquet N, Appelman B, Lavell AA, van Vught LA, Burger JA, Poniman M, Oomen M, Eggink D, Bijl TP, van Willigen HD, Wynberg E, Verkaik BJ, Figaroa OJ, de Vries PJ, Boertien TM; Amsterdam UMC COVID-19 S3/HCW study group; Bomers MK, Sikkens JJ, Le Grand R, de Jong MD, Prins M, Chung AW, de Bree GJ, Sanders RW, van Gils MJ. Grobben M, et al. Elife. 2021 Nov 23;10:e70330. doi: 10.7554/eLife.70330. Elife. 2021. PMID: 34812143 Free PMC article.
Comparative analysis of spike-specific IgG Fc glycoprofiles elicited by adenoviral, mRNA, and protein-based SARS-CoV-2 vaccines.
Van Coillie J, Pongracz T, Šuštić T, Wang W, Nouta J, Le Gars M, Keijzer S, Linty F, Cristianawati O, Keijser JBD, Visser R, van Vught LA, Slim MA, van Mourik N, Smit MJ, Sander A, Schmidt DE, Steenhuis M, Rispens T, Nielsen MA, Mordmüller BG, Vlaar APJ, Ellen van der Schoot C, Roozendaal R, Wuhrer M, Vidarsson G; UMC COVID-19 S3/HCW study group; Fatebenefratelli-Sacco Infectious Diseases Physicians group; Radboud University Medical Center (RUMC) and COUGH1 study group. Van Coillie J, et al. iScience. 2023 Aug 14;26(9):107619. doi: 10.1016/j.isci.2023.107619. eCollection 2023 Sep 15. iScience. 2023. PMID: 37670790 Free PMC article.
The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees.
Van Coillie J, Pongracz T, Rahmöller J, Chen HJ, Geyer CE, van Vught LA, Buhre JS, Šuštić T, van Osch TLJ, Steenhuis M, Hoepel W, Wang W, Lixenfeld AS, Nouta J, Keijzer S, Linty F, Visser R, Larsen MD, Martin EL, Künsting I, Lehrian S, von Kopylow V, Kern C, Lunding HB, de Winther M, van Mourik N, Rispens T, Graf T, Slim MA, Minnaar RP, Bomers MK, Sikkens JJ, Vlaar APJ, van der Schoot CE, den Dunnen J, Wuhrer M, Ehlers M, Vidarsson G; Fatebenefratelli-Sacco Infectious Diseases Physicians group; UMC COVID-19 S3/HCW study group. Van Coillie J, et al. EBioMedicine. 2023 Jan;87:104408. doi: 10.1016/j.ebiom.2022.104408. Epub 2022 Dec 16. EBioMedicine. 2023. PMID: 36529104 Free PMC article.
Pharmacokinetic analysis of vilobelimab, anaphylatoxin C5a and antidrug antibodies in PANAMO: a phase 3 study in critically ill,  invasively mechanically ventilated COVID-19 patients.
Lim EHT, Vlaar APJ, de Bruin S, Rückinger S, Thielert C, Habel M, Guo R, Burnett BP, Dickinson J, Brouwer MC, Riedemann NC, van de Beek D; PANAMO study group. Lim EHT, et al. Intensive Care Med Exp. 2023 Jun 19;11(1):37. doi: 10.1186/s40635-023-00520-8. Intensive Care Med Exp. 2023. PMID: 37332066 Free PMC article.
20 results