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Galactosylated Pro-Drug of Ursodeoxycholic Acid: Design, Synthesis, Characterization, and Pharmacological Effects in a Rat Model of Estrogen-Induced Cholestasis.
Di Guida F, Pirozzi C, Magliocca S, Santoro A, Lama A, Russo R, Nieddu M, Burrai L, Boatto G, Mollica MP, Sodano F, Lazzarato L, Chegaev K, Meli R, Raso GM, Rimoli MG. Di Guida F, et al. Among authors: chegaev k. Mol Pharm. 2018 Jan 2;15(1):21-30. doi: 10.1021/acs.molpharmaceut.7b00626. Epub 2017 Nov 28. Mol Pharm. 2018. PMID: 29140706 Free article.
Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity.
Dos Santos Fernandes GF, de Souza PC, Moreno-Viguri E, Santivañez-Veliz M, Paucar R, Pérez-Silanes S, Chegaev K, Guglielmo S, Lazzarato L, Fruttero R, Man Chin C, da Silva PB, Chorilli M, Solcia MC, Ribeiro CM, Silva CSP, Marino LB, Bosquesi PL, Hunt DM, de Carvalho LPS, de Souza Costa CA, Cho SH, Wang Y, Franzblau SG, Pavan FR, Dos Santos JL. Dos Santos Fernandes GF, et al. Among authors: chegaev k. J Med Chem. 2017 Oct 26;60(20):8647-8660. doi: 10.1021/acs.jmedchem.7b01332. Epub 2017 Oct 16. J Med Chem. 2017. PMID: 28968083 Free PMC article.
Aceclofenac-Galactose Conjugate: Design, Synthesis, Characterization, and Pharmacological and Toxicological Evaluations.
Magliocca S, De Caro C, Lazzarato L, Russo R, Rolando B, Chegaev K, Marini E, Nieddu M, Burrai L, Boatto G, Cristiano C, Marabello D, Gazzano E, Riganti C, Sodano F, Rimoli MG. Magliocca S, et al. Among authors: chegaev k. Mol Pharm. 2018 Aug 6;15(8):3101-3110. doi: 10.1021/acs.molpharmaceut.8b00195. Epub 2018 Jun 27. Mol Pharm. 2018. PMID: 29912563
Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug.
Sodano F, Lazzarato L, Rolando B, Spyrakis F, De Caro C, Magliocca S, Marabello D, Chegaev K, Gazzano E, Riganti C, Calignano A, Russo R, Rimoli MG. Sodano F, et al. Among authors: chegaev k. Mol Pharm. 2019 Oct 7;16(10):4181-4189. doi: 10.1021/acs.molpharmaceut.9b00508. Epub 2019 Sep 12. Mol Pharm. 2019. PMID: 31465230 Free article.
Doxorubicin-antioxidant co-drugs.
Chegaev K, Riganti C, Rolando B, Lazzarato L, Gazzano E, Guglielmo S, Ghigo D, Fruttero R, Gasco A. Chegaev K, et al. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5307-10. doi: 10.1016/j.bmcl.2013.07.070. Epub 2013 Aug 8. Bioorg Med Chem Lett. 2013. PMID: 23973213 Free article.
58 results