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Phosphanegold(I) dithiocarbamates, R3PAu[SC(=S)N((i)Pr)CH2CH2OH] for R = Ph, Cy and Et: role of phosphane-bound R substituents upon in vitro cytotoxicity against MCF-7R breast cancer cells and cell death pathways.
Jamaludin NS, Goh ZJ, Cheah YK, Ang KP, Sim JH, Khoo CH, Fairuz ZA, Halim SN, Ng SW, Seng HL, Tiekink ER. Jamaludin NS, et al. Among authors: cheah yk. Eur J Med Chem. 2013 Sep;67:127-41. doi: 10.1016/j.ejmech.2013.06.038. Epub 2013 Jun 26. Eur J Med Chem. 2013. PMID: 23856069
Phosphanegold(I) thiolates, Ph3PAu[SC(OR)=NC 6H 4Me-4] for R = Me, Et and iPr, induce apoptosis, cell cycle arrest and inhibit cell invasion of HT-29 colon cancer cells through modulation of the nuclear factor-κB activation pathway and ubiquitination.
Ooi KK, Yeo CI, Ang KP, Akim AM, Cheah YK, Halim SN, Seng HL, Tiekink ER. Ooi KK, et al. Among authors: cheah yk. J Biol Inorg Chem. 2015 Jul;20(5):855-73. doi: 10.1007/s00775-015-1271-5. Epub 2015 May 24. J Biol Inorg Chem. 2015. PMID: 26003312
121 results