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Multiomics integration of 22 immune-mediated monogenic diseases reveals an emergent axis of human immune health.
Sparks R, Rachmaninoff N, Hirsch DC, Bansal N, Lau WW, Martins AJ, Chen J, Liu CC, Cheung F, Failla LE, Biancotto A, Fantoni G, Sellers BA, Chawla DG, Howe KN, Mostaghimi D, Farmer R, Kotliarov Y, Calvo KR, Palmer C, Daub J, Foruraghi L, Kreuzburg S, Treat J, Urban AK, Jones A, Romeo T, Deuitch NT, Moura NS, Weinstein B, Moir S, Ferrucci L, Barron KS, Aksentijevich I, Kleinstein SH, Townsley DM, Young NS, Frischmeyer-Guerrerio PA, Uzel G, Pinto-Patarroyo GP, Cudrici CD, Hoffmann P, Stone DL, Ombrello AK, Freeman AF, Zerbe CS, Kastner DL, Holland SM, Tsang JS. Sparks R, et al. Among authors: chawla dg. Res Sq [Preprint]. 2023 Mar 20:rs.3.rs-2070975. doi: 10.21203/rs.3.rs-2070975/v1. Res Sq. 2023. PMID: 36993430 Free PMC article. Preprint.
The Immune Signatures data resource, a compendium of systems vaccinology datasets.
Diray-Arce J, Miller HER, Henrich E, Gerritsen B, Mulè MP, Fourati S, Gygi J, Hagan T, Tomalin L, Rychkov D, Kazmin D, Chawla DG, Meng H, Dunn P, Campbell J; Human Immunology Project Consortium (HIPC); Sarwal M, Tsang JS, Levy O, Pulendran B, Sekaly R, Floratos A, Gottardo R, Kleinstein SH, Suárez-Fariñas M. Diray-Arce J, et al. Among authors: chawla dg. Sci Data. 2022 Oct 20;9(1):635. doi: 10.1038/s41597-022-01714-7. Sci Data. 2022. PMID: 36266291 Free PMC article.
Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses.
Hagan T, Gerritsen B, Tomalin LE, Fourati S, Mulè MP, Chawla DG, Rychkov D, Henrich E, Miller HER, Diray-Arce J, Dunn P, Lee A; Human Immunology Project Consortium (HIPC); Levy O, Gottardo R, Sarwal MM, Tsang JS, Suárez-Fariñas M, Sékaly RP, Kleinstein SH, Pulendran B. Hagan T, et al. Among authors: chawla dg. Nat Immunol. 2022 Dec;23(12):1788-1798. doi: 10.1038/s41590-022-01328-6. Epub 2022 Oct 31. Nat Immunol. 2022. PMID: 36316475 Free PMC article.
Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination.
Fourati S, Tomalin LE, Mulè MP, Chawla DG, Gerritsen B, Rychkov D, Henrich E, Miller HER, Hagan T, Diray-Arce J, Dunn P; Human Immunology Project Consortium (HIPC); Levy O, Gottardo R, Sarwal MM, Tsang JS, Suárez-Fariñas M, Pulendran B, Kleinstein SH, Sékaly RP. Fourati S, et al. Among authors: chawla dg. Nat Immunol. 2022 Dec;23(12):1777-1787. doi: 10.1038/s41590-022-01329-5. Epub 2022 Oct 31. Nat Immunol. 2022. PMID: 36316476 Free PMC article.
A curated collection of human vaccination response signatures.
Smith KC, Chawla DG, Dhillon BK, Ji Z, Vita R, van der Leest EC, Weng JYJ, Tang E, Abid A; Human Immunology Project Consortium (HIPC); Peters B, Hancock REW, Floratos A, Kleinstein SH. Smith KC, et al. Among authors: chawla dg. Sci Data. 2022 Nov 8;9(1):678. doi: 10.1038/s41597-022-01558-1. Sci Data. 2022. PMID: 36347894 Free PMC article.
Platelet response to influenza vaccination reflects effects of aging.
Konstorum A, Mohanty S, Zhao Y, Melillo A, Vander Wyk B, Nelson A, Tsang S, Blevins TP, Belshe RB, Chawla DG, Rondina MT, Gill TM, Montgomery RR, Allore HG, Kleinstein SH, Shaw AC. Konstorum A, et al. Among authors: chawla dg. Aging Cell. 2023 Feb;22(2):e13749. doi: 10.1111/acel.13749. Epub 2023 Jan 19. Aging Cell. 2023. PMID: 36656789 Free PMC article.
Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data.
Chen X, Wang Y, Cappuccio A, Cheng WS, Zamojski FR, Nair VD, Miller CM, Rubenstein AB, Nudelman G, Tadych A, Theesfeld CL, Vornholt A, George MC, Ruffin F, Dagher M, Chawla DG, Soares-Schanoski A, Spurbeck RR, Ndhlovu LC, Sebra R, Kleinstein SH, Letizia AG, Ramos I, Fowler VG Jr, Woods CW, Zaslavsky E, Troyanskaya OG, Sealfon SC. Chen X, et al. Among authors: chawla dg. Nat Comput Sci. 2023 Jul;3(7):644-657. doi: 10.1038/s43588-023-00476-5. Epub 2023 Jul 25. Nat Comput Sci. 2023. PMID: 37974651 Free PMC article.
13 results