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Dehydrobufotenin extracted from the Amazonian toad Rhinella marina (Anura: Bufonidae) as a prototype molecule for the development of antiplasmodial drugs.
Banfi FF, Krombauer GC, da Fonseca AL, Nunes RR, Andrade SN, de Rezende MA, Chaves MH, Monção EDS, Taranto AG, Rodrigues DJ, Vieira GM, de Castro WV, Varotti FP, Sanchez BAM. Banfi FF, et al. Among authors: chaves mh. J Venom Anim Toxins Incl Trop Dis. 2021 Jan 8;27:e20200073. doi: 10.1590/1678-9199-JVATITD-2020-0073. eCollection 2021. J Venom Anim Toxins Incl Trop Dis. 2021. PMID: 33519927 Free PMC article.
Marinobufagin, a molecule from poisonous frogs, causes biochemical, morphological and cell cycle changes in human neoplasms and vegetal cells.
Machado KDC, Sousa LQ, Lima DJB, Soares BM, Cavalcanti BC, Maranhão SS, Noronha JDC, Rodrigues DJ, Militão GCG, Chaves MH, Vieira-Júnior GM, Pessoa C, Moraes MO, Sousa JMCE, Melo-Cavalcante AAC, Ferreira PMP. Machado KDC, et al. Among authors: chaves mh. Toxicol Lett. 2018 Mar 15;285:121-131. doi: 10.1016/j.toxlet.2017.12.018. Epub 2017 Dec 26. Toxicol Lett. 2018. PMID: 29287997
New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells.
Garcia IJP, de Oliveira GC, de Moura Valadares JM, Banfi FF, Andrade SN, Freitas TR, Dos Santos Monção Filho E, Lima Santos H, Júnior GMV, Chaves MH, de Jesus Rodrigues D, Sanchez BAM, Varotti FP, Barbosa LA. Garcia IJP, et al. Among authors: chaves mh. Steroids. 2019 Dec;152:108490. doi: 10.1016/j.steroids.2019.108490. Epub 2019 Sep 6. Steroids. 2019. PMID: 31499071
Toxic profile of marinobufagin from poisonous Amazon toads and antitumoral effects on human colorectal carcinomas.
Ferreira PMP, Sousa LQ, Sousa RWR, Rodrigues DJ, Monção Filho EDS, Chaves MH, Vieira Júnior GM, Rizzo MDS, Filgueiras LA, Mendes AN, Lima DJB, Pessoa C, Sousa JMCE, Rodrigues ACBDC, Soares MBP, Bezerra DP. Ferreira PMP, et al. Among authors: chaves mh. J Ethnopharmacol. 2023 Jun 28;310:116406. doi: 10.1016/j.jep.2023.116406. Epub 2023 Mar 23. J Ethnopharmacol. 2023. PMID: 36965547
Comparative study of composition of methanolic extracts of the paratoid gland secretions (PGS) of Rhinella jimi (cururu toad) from northeastern Brazil: Gender, seasonality and geographic occurrence.
Sousa Barros ED, Santos Monção Filho ED, Fonseca Pio YP, Amorim MR, Berlinck RGS, Cássia Moura R, Fonseca MG, Dantas C, Coelho RC, Silva GRD, Chaves MH, Vieira Júnior GM. Sousa Barros ED, et al. Among authors: chaves mh. Toxicon. 2022 Jul 30;214:37-46. doi: 10.1016/j.toxicon.2022.04.020. Epub 2022 May 11. Toxicon. 2022. PMID: 35562061 Free article.
Toxicological, chemopreventive, and cytotoxic potentialities of rare vegetal species and supporting findings for the Brazilian Unified Health System (SUS).
Silva JDN, Monção NBN, de Farias RRS, Citó AMDGL, Chaves MH, Araújo MRS, Lima DJB, Pessoa C, Lima A, Araújo ECDC, Militão GCG, Costa MPD, Capasso R, Ferreira PMP. Silva JDN, et al. Among authors: chaves mh. J Toxicol Environ Health A. 2020 Jul 17;83(13-14):525-545. doi: 10.1080/15287394.2020.1780658. Epub 2020 Jun 22. J Toxicol Environ Health A. 2020. PMID: 32568625
68 results