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Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model.
Do TM, Capdevila C, Pradier L, Blanchard V, Lopez-Grancha M, Schussler N, Steinmetz A, Beninga J, Boulay D, Dugay P, Verdier P, Aubin N, Dargazanli G, Chaves C, Genet E, Lossouarn Y, Loux C, Michoux F, Moindrot N, Chanut F, Gury T, Eyquem S, Valente D, Bergis O, Rao E, Lesuisse D. Do TM, et al. Among authors: chaves c. Mol Ther Methods Clin Dev. 2020 Aug 21;19:58-77. doi: 10.1016/j.omtm.2020.08.014. eCollection 2020 Dec 11. Mol Ther Methods Clin Dev. 2020. PMID: 33005703 Free PMC article.
Exploring ITM2A as a new potential target for brain delivery.
Cegarra C, Chaves C, Déon C, Do TM, Dumas B, Frenzel A, Kuhn P, Roudieres V, Guillemot JC, Lesuisse D. Cegarra C, et al. Among authors: chaves c. Fluids Barriers CNS. 2022 Mar 21;19(1):25. doi: 10.1186/s12987-022-00321-3. Fluids Barriers CNS. 2022. PMID: 35313913 Free PMC article.
The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier.
Kurtyka M, Wessely F, Bau S, Ifie E, He L, de Wit NM, Pedersen ABV, Keller M, Webber C, de Vries HE, Ansorge O, Betsholtz C, De Bock M, Chaves C, Brodin B, Nielsen MS, Neuhaus W, Bell RD, Letoha T, Meyer AH, Leparc G, Lenter M, Lesuisse D, Cader ZM, Buckley ST, Loryan I, Pietrzik CU. Kurtyka M, et al. Among authors: chaves c. Eur J Cell Biol. 2024 Mar 21;103(2):151406. doi: 10.1016/j.ejcb.2024.151406. Online ahead of print. Eur J Cell Biol. 2024. PMID: 38547677 Free article.
Targeted unlabeled multiple reaction monitoring analysis of cell markers for the study of sample heterogeneity in isolated rat brain cortical microvessels.
Gomez-Zepeda D, Chaves C, Taghi M, Sergent P, Liu WQ, Chhuon C, Vidal M, Picard M, Thioulouse E, Broutin I, Guerrera IC, Scherrmann JM, Parmentier Y, Decleves X, Menet MC. Gomez-Zepeda D, et al. Among authors: chaves c. J Neurochem. 2017 Aug;142(4):597-609. doi: 10.1111/jnc.14095. Epub 2017 Jul 11. J Neurochem. 2017. PMID: 28581635 Free article.
397 results