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The RNA binding protein human antigen R is a gatekeeper of liver homeostasis.
Subramanian P, Gargani S, Palladini A, Chatzimike M, Grzybek M, Peitzsch M, Papanastasiou AD, Pyrina I, Ntafis V, Gercken B, Lesche M, Petzold A, Sinha A, Nati M, Thangapandi VR, Kourtzelis I, Andreadou M, Witt A, Dahl A, Burkhardt R, Haase R, Domingues AMJ, Henry I, Zamboni N, Mirtschink P, Chung KJ, Hampe J, Coskun Ü, Kontoyiannis DL, Chavakis T. Subramanian P, et al. Among authors: chavakis t. Hepatology. 2022 Apr;75(4):881-897. doi: 10.1002/hep.32153. Epub 2021 Dec 5. Hepatology. 2022. PMID: 34519101 Free article.
The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance.
Phieler J, Chung KJ, Chatzigeorgiou A, Klotzsche-von Ameln A, Garcia-Martin R, Sprott D, Moisidou M, Tzanavari T, Ludwig B, Baraban E, Ehrhart-Bornstein M, Bornstein SR, Mziaut H, Solimena M, Karalis KP, Economopoulou M, Lambris JD, Chavakis T. Phieler J, et al. Among authors: chavakis t. J Immunol. 2013 Oct 15;191(8):4367-74. doi: 10.4049/jimmunol.1300038. Epub 2013 Sep 16. J Immunol. 2013. PMID: 24043887 Free PMC article.
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte KM, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E. Chatzigeorgiou A, et al. Among authors: chavakis t. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2686-91. doi: 10.1073/pnas.1400419111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24492375 Free PMC article.
Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation.
Chatzigeorgiou A, Chung KJ, Garcia-Martin R, Alexaki VI, Klotzsche-von Ameln A, Phieler J, Sprott D, Kanczkowski W, Tzanavari T, Bdeir M, Bergmann S, Cartellieri M, Bachmann M, Nikolakopoulou P, Androutsellis-Theotokis A, Siegert G, Bornstein SR, Muders MH, Boon L, Karalis KP, Lutgens E, Chavakis T. Chatzigeorgiou A, et al. Among authors: chavakis t. Hepatology. 2014 Oct;60(4):1196-210. doi: 10.1002/hep.27233. Epub 2014 Aug 21. Hepatology. 2014. PMID: 24845056
Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.
Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, Ranjan S, Wolter J, Kohli S, Shahzad K, Heidel F, Krueger M, Schwenger V, Moeller MJ, Kalinski T, Reiser J, Chavakis T, Isermann B. Madhusudhan T, et al. Among authors: chavakis t. Nat Commun. 2015 Mar 10;6:6496. doi: 10.1038/ncomms7496. Nat Commun. 2015. PMID: 25754093 Free PMC article.
293 results